Iain A. McNeish

Imperial College Healthcare NHS Trust — United Kingdom

Medicine · Health Sciences

70h-index34.7kcitations774works5.32yr avg
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Research Topics

Ovarian cancer diagnosis and treatment(353), PARP inhibition in cancer therapy(125), Virus-based gene therapy research(108), CRISPR and Genetic Engineering(86), Cancer Genomics and Diagnostics(70)

Publications747 total

Assessing PARP trapping dynamics in ovarian cancer using a CRISPR-engineered FRET biosensor
Cell Reports Methods·2025Open Access
RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination
Communications Biology·2025Open Access
Somatic evolution following cancer treatment in normal tissue
Nature·2025Open Access
Vinorelbine enhances the efficacy of oncolytic vaccinia virus in a preclinical model of ovarian high-grade serous carcinoma
Molecular Therapy Oncology·2025Open Access
Figure 6 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Figure 2 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Figure 1 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Figure 4 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Figure 5 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Figure 3 from Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma
2025Open Access
Supplementary Data from Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
2025Open Access
Supplementary Data from Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
2025Open Access
Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer
npj Genomic Medicine·2025Open Access
Cancer-selective targeting of the NF-κB pathway via GADD45β/MKK7 inhibition: Results from the phase I trial of the first-in-class inhibitor, DTP3, in patients with relapsed or refractory multiple myeloma
Blood·2025Open Access
Clinical validation of a <scp>DNA</scp> methylation biomarker associated with overall survival of relapsed ovarian cancer patients
International Journal of Cancer·2025Open Access
Identification of actionable targets using <scp>DEPArray</scp> ‐based sorting of pure carcinoma and stromal populations from formalin‐fixed paraffin‐embedded tissues followed by shallow whole‐genome sequencing
The Journal of Pathology·2025Open Access
Identifying high-risk relapse in early-stage I to II ovarian cancer using the CA125 ELIMination rate constant K (KELIM) score: a Gynecologic Cancer InterGroup individual patient-data meta-analysis
International Journal of Gynecological Cancer·2025· 1 citedOpen Access
Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma
2025Open Access
Beyond <i>BRCA</i> deficiency: Clinical and molecular predictors of survival in patients with <i>BRCA</i> -deficient tubo-ovarian high-grade serous carcinoma
2025Open Access
Abstract A038: Monitoring PARP trapping in live ovarian cancer cells using a CRISPR-engineered FRET biosensor
Cancer Research·2025
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Frequent Co-authors

Amit M. Oza(11), Ana Oaknin(11), Ignace Vergote(11), James D. Brenton(11), Nicoletta Colombo(10), Isabelle Ray‐Coquard(10), Rosalind Glasspool(10), Domenica Lorusso(9), Jonathan A. Ledermann(9), Robert L. Coleman(8), Alexandra Léary(8), David M. O’Malley(8), Elizabeth M. Swisher(8), Clare L. Scott(8), Hani Gabra(8), Heidi Giordano(7), Sandro Pignata(7), Frances R. Balkwill(7), Anna V. Tinker(7), Andrew R. Clamp(6)