Gary J. Brouhard

McGill University — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index4.3kcitations68works3.72yr avg
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Research Topics

Microtubule and mitosis dynamics(58), Photosynthetic Processes and Mechanisms(16), Genomics and Chromatin Dynamics(12), Cellular Mechanics and Interactions(10), Ubiquitin and proteasome pathways(6)

Publications68 total

Competition for microtubule lattice spacing between a microtubule expander and compactor
Current Biology·2025· 5 cited
Conformational flexibility of tubulin dimers regulates the transitions of microtubule dynamic instability
2025· 2 citedOpen Access
Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1
Current Biology·2025· 10 cited
Competition for microtubule lattice spacing between a microtubule expander and compactor
2025· 2 citedOpen Access
Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation
Nature Communications·2025· 10 citedOpen Access
Competition for Microtubule Lattice Spacing between a Microtubule Expander and Compactor
SSRN Electronic Journal·2025· 1 citedOpen Access
Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1
2024· 6 citedOpen Access
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation
Molecular Biology of the Cell·2024· 1 citedOpen Access
Microtubule dynamic instability is sensitive to specific biological viscogens <i>in vitro</i>
2024· 3 citedOpen Access
Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment
2024· 1 citedOpen Access
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation
2024Open Access
The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity
Molecular Biology of the Cell·2023· 8 citedOpen Access
Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation
2023· 6 citedOpen Access
Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain
eLife·2022· 18 citedOpen Access
Author response: Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain
2022Open Access
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
Developmental Cell·2022· 152 citedOpen Access
The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization
2021· 3 citedOpen Access
Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain
2021Open Access
Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding
Structure·2021· 27 citedOpen Access
Cytoplasm Biophysical Properties Limit Cytoskeleton Dynamics In Vivo
Biophysical Journal·2021Open Access
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Frequent Co-authors

Susanne Bechstedt(11), Adam G. Hendricks(9), Sami Chaaban(7), Muriel Sébastien(7), Michał W. Wieczorek(6), Sofía Cruz Tetlalmatzi(6), Alexandra Paquette(6), Khanh Huy Bui(5), Jawdat Al‐Bassam(4), Jonathon Howard(4), Fred Chang(4), Claire H. Edrington(4), Chieh-Ting Hsu(4), Corbin Black(4), Jeffrey H. Stear(3), Arthur T. Molines(3), David Sept(3), Paul W. Wiseman(3), Jean‐François Trempe(3), Wang Peng(3)