David Barford

MRC Laboratory of Molecular Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

81h-index26.1kcitations285works3.82yr avg
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Research Topics

Microtubule and mitosis dynamics(102), Ubiquitin and proteasome pathways(57), Protein Tyrosine Phosphatases(41), Photosynthetic Processes and Mechanisms(33), Enzyme Structure and Function(30)

Publications285 total

Models for the architecture of the human inner kinetochore CCAN complex on centromeric α-satellite CENP-A nucleosome arrays
2025· 1 citedOpen Access
Author response: Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
2025Open Access
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
eLife·2025Open Access
Assembly and phospho-regulatory mechanisms of the budding yeast outer kinetochore KMN complex
2025Open Access
Author response: Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Molecular mechanism of <scp>Mad2</scp> conformational conversion promoted by the <scp>Mad2</scp> ‐interaction motif of <scp>Cdc20</scp>
Protein Science·2025· 3 citedOpen Access
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
eLife·2025· 3 citedOpen Access
Author response: Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
Nature Communications·2024· 8 citedOpen Access
Human spermatogenesis leads to a reduced nuclear pore structure and function
2024· 7 citedOpen Access
A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
eLife·2024· 3 citedOpen Access
Author response: A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
2024Open Access
A comparative study of the cryo-EM structures of S. cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
2024Open Access
Author response: A comparative study of the cryo-EM structures of S. cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
2024Open Access
A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
eLife·2024· 2 citedOpen Access
A comparative study of the cryo-EM structures of S. cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
2024Open Access
A comparative study of the cryo-EM structures of <i>S. cerevisiae</i> and human anaphase-promoting complex/cyclosome (APC/C)
2024· 2 citedOpen Access
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2024Open Access
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Frequent Co-authors

Ziguo Zhang(9), Nicholas K. Tonks(7), Jing Yang(7), S. Mark Roe(5), Annette Salmeen(4), Andrew Flint(4), Brian A. Hemmings(4), L.N. Johnson(4), Leifu Chang(4), Valerie M. Good(3), Jannik N. Andersen(3), Michael P. Myers(3), Amit Kumar Das(3), David Komander(3), J.S. Parker(3), Eric H. Kong(3), Claudio Alfieri(3), Mathew J. Garnett(2), Richard Marais(2), Marie-Pierre Egloff(2)