Jerry Siu

Amgen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index164citations7works0.02yr avg
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Research Topics

Sphingolipid Metabolism and Signaling(5), Carbohydrate Chemistry and Synthesis(2), Protein Tyrosine Phosphatases(2), Protein Kinase Regulation and GTPase Signaling(1), Lipid Membrane Structure and Behavior(1)

Publications7 total

Predictability of Peripheral Lymphocyte Reduction of Novel S1P1 Agonists by In Vitro GPCR Signaling Profile
SLAS DISCOVERY·2013· 5 citedOpen Access
Novel 5- and 6-subtituted benzothiazoles with improved physicochemical properties: Potent S1P1 agonists with in vivo lymphocyte-depleting activity
Bioorganic & Medicinal Chemistry Letters·2011· 9 citedOpen Access
Discovery of AMG 369, a Thiazolo[5,4-<i>b</i>]pyridine Agonist of S1P<sub>1</sub> and S1P<sub>5</sub>
ACS Medicinal Chemistry Letters·2010· 54 citedOpen Access
Discovery of a Potent, S1P<sub>3</sub>-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P<sub>1</sub>)
ACS Medicinal Chemistry Letters·2010· 19 citedOpen Access
Benzofuran Derivatives as Potent, Orally Active S1P<sub>1</sub> Receptor Agonists: A Preclinical Lead Molecule for MS
ACS Medicinal Chemistry Letters·2010· 37 citedOpen Access
B7RP-1-ICOS Interactions Are Required for Optimal Infection-Induced Expansion of CD4+ Th1 and Th2 Responses
The Journal of Immunology·2006· 38 citedOpen Access
Two tales of T cells
Cell·1990· 2 cited

Frequent Co-authors

Michele McElvain(5), Han Xu(5), Roland W. Bürli(5), Victor J. Cee(4), Mike Fiorino(4), Scot Middleton(4), Michael Schrag(4), Yang Xu(4), Mike Frohn(3), Brian A. Lanman(3), Jennifer E. Golden(3), Kristine Muller(3), Janet Buys(3), Michelle Horner(3), Dalia Rivenzon‐Segal(3), Hugo M. Vargas(3), Susana Neira(2), Anu Gore(2), Andrea Itano(2), Xuxia Zhang(2)