Abraham M. Lenhoff

University of Delaware — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

63h-index13.8kcitations251works2.42yr avg
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Research Topics

Protein purification and stability(103), Enzyme Structure and Function(50), Protein Structure and Dynamics(45), Microfluidic and Capillary Electrophoresis Applications(38), Analytical Chemistry and Chromatography(38)

Publications251 total

Role of viral protein ratio in the structure and separation of empty and full adeno-associated virus capsids: A molecular dynamics study
Molecular Therapy Advances·2025Open Access
Modernizing the platform process of antibody purification for enhanced impurity clearance
Separation and Purification Technology·2025· 1 citedOpen Access
High-Pressure Rheology of a Thermoreversible Protein Sol–Gel
Industrial & Engineering Chemistry Research·2025
Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells
Frontiers in Immunology·2025Open Access
Molecular origins of high viscosity in concentrated solutions of monoclonal antibodies
Biophysical Journal·2025Open Access
Multi-component behavior of host-cell protein- and antibody-containing heteroaggregates in protein A chromatography
Journal of Chromatography A·2025· 1 cited
Influence of Pressure Holding Time on Ovalbumin Solution Behavior via Small‐Angle Neutron Scattering and Diffusing Wave Spectroscopy
Journal of Food Process Engineering·2025· 2 citedOpen Access
Coupling high‐throughput and modeling approaches to streamline early‐stage process development for biologics
Biotechnology Progress·2025· 5 cited
Modernizing the platform process of antibody purification for enhanced impurity clearance
SSRN Electronic Journal·2025Open Access
Computational modelling of cardiac control following myocardial infarction using an <i>in silico</i> patient cohort
The Journal of Physiology·2024· 2 citedOpen Access
Engineering of heterobifunctional biopolymers for tunable binding and precipitation of Strep‐Tag proteins and virus‐like nanoparticles
Biotechnology and Bioengineering·2024· 1 citedOpen Access
High‐throughput in silico workflow for optimization and characterization of multimodal chromatographic processes
Biotechnology Progress·2024· 14 cited
Modeling and Analysis of Central and Peripheral Autonomic Contributions to Decreased Cardiac Vagal Tone Following Myocardial Infarction
Physiology·2024
Author response for "High‐throughput in silico workflow for optimization and characterization of multimodal chromatographic processes"
2024
Biotechnology and Bioengineering: Volume 121, Number 4, April 2024
Biotechnology and Bioengineering·2024Open Access
Modeling scalability of impurity precipitation in downstream biomanufacturing
Biotechnology Progress·2024
Factors affecting product association as a mechanism of host‐cell protein persistence in bioprocessing
Biotechnology and Bioengineering·2024· 8 cited
Application of mechanistic modelling in membrane and fiber chromatography for purification of biotherapeutics — A review
Journal of Chromatography A·2024· 9 citedOpen Access
Combined Effects of Pressure and Ionic Strength on Protein–Protein Interactions: An Empirical Approach
Biomacromolecules·2023· 5 citedOpen Access
Predictive mechanistic modeling of loading and elution in protein A chromatography
Journal of Chromatography A·2023· 12 cited
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Frequent Co-authors

Orlin D. Velev(10), Eric W. Kaler(6), Peter M. Tessier(5), E. W. Kaler(4), Charles M. Roth(4), Stanley I. Sandler(4), Kristin N. Valente(4), Kelvin H. Lee(4), B.L. Neal(3), D. Asthagiri(3), André C. Dumetz(3), Nicholas E. Levy(3), Matthew R. Oberholzer(3), T. A. Jede(2), Raúl F. Lobo(2), Anand T. Kalambur(2), John F. Rabolt(2), Peter DePhillips(2), Aaron M. Chockla(2), Byung Jun Yoon(2)