Susanna Grönberg-Vähä-Koskela

University of Helsinki — Finland

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index446citations46works5.82yr avg
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Research Topics

Virus-based gene therapy research(45), CAR-T cell therapy research(44), Cancer Research and Treatments(22), Viral Infectious Diseases and Gene Expression in Insects(11), Immunotherapy and Immune Responses(6)

Publications46 total

Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors
Molecular Therapy·2026Open Access
Oncolytic adenovirus encoding variant interleukin-2 combined with chemotherapy enables PD-L1 inhibition in pancreatic cancer models
Cancer Immunology Immunotherapy·2025· 2 citedOpen Access
Boosting anti-tumor immunity with TILT-517 oncolytic adenovirus and checkpoint blockade in renal cell carcinoma
Molecular Therapy Oncology·2025· 3 citedOpen Access
The oncolytic adenovirus TILT-123 with pembrolizumab in platinum resistant or refractory ovarian cancer: the phase 1a PROTA trial
Nature Communications·2025· 15 citedOpen Access
Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine
Molecular Therapy·2024· 1 citedOpen Access
Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine
Molecular Therapy·2024· 14 citedOpen Access
Boosting cytotoxicity of adoptive allogeneic NK cell therapy with an oncolytic adenovirus encoding a human vIL-2 cytokine for the treatment of human ovarian cancer
Cancer Gene Therapy·2023· 10 citedOpen Access
805 Oncolytic adenovirus encoding human interleukin-7 in combination with ICIs as a treatment strategy against renal cell carcinoma (RCC)
Regular and Young Investigator Award Abstracts·2023Open Access
814 Enhancing anti-tumor response in ICI-refractory non-small cell lung cancer through intravenous administration of oncolytic adenovirus armed with hTNFα and hIL-2 in combination with aPD-1 blockade
Regular and Young Investigator Award Abstracts·2023Open Access
806 Oncolytic adenovirus coding for human Mucin1 T cell engager with interleukin-2 potentiates anti-tumor T cell responses against tumors
Regular and Young Investigator Award Abstracts·2023Open Access
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine
Cancer Gene Therapy·2023· 11 citedOpen Access
An oncolytic adenovirus coding for a variant interleukin 2 cytokine improves response to chemotherapy through enhancement of effector lymphocyte cytotoxicity, fibroblast compartment modulation and mitotic slippage
Frontiers in Immunology·2023· 4 citedOpen Access
Supplementary Figure 5 from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Data from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Supplementary Materials and Methods from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Supplementary Figure 5 from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Data from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Supplementary Figure 2 from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Supplementary Figure Legends from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
Supplementary Figure 1 from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
2023Open Access
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Frequent Co-authors

Akseli Hemminki(43), Siri Tähtinen(24), Mikko Siurala(23), Markus Vähä‐Koskela(23), Maiju Merisalo-Soikkeli(22), Dave Lumén(21), Anu J. Airaksinen(21), João M. Santos(19), Víctor Cervera-Carrascón(19), Tatiana V. Kudling(18), James H.A. Clubb(17), Dafne C.A. Quixabeira(16), Saru Basnet(16), Victor Arias(16), Santeri A. Pakola(15), Riikka Havunen(14), Anna Kanerva(14), Lyna Haybout(10), Otto Hemminki(9), Camilla Heiniö(9)