Axel Bouchon

Bayer (Germany) — Germany

Immunology and Microbiology · Life Sciences

13h-index4.2kcitations17works0.02yr avg
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Research Topics

Inflammation biomarkers and pathways(10), Immune Cell Function and Interaction(4), Cell death mechanisms and regulation(3), Sepsis Diagnosis and Treatment(2), Immunotherapy and Immune Responses(2)

Publications17 total

Soluble TREM-1 is not suitable for distinguishing between systemic inflammatory response syndrome and sepsis survivors and nonsurvivors in the early stage of acute inflammation
European Journal of Anaesthesiology·2009· 58 cited
TREM-1–expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases
Journal of Clinical Investigation·2007· 367 citedOpen Access
sTREM-1 is not suitable to discriminate survivors and nonsurvivors in surgical patients with severe sepsis or septic shock
Critical Care·2007Open Access
Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis
Critical Care·2007· 127 citedOpen Access
Macrophages Expressing Triggering Receptor Expressed on Myeloid Cells-1 Are Underrepresented in the Human Intestine
The Journal of Immunology·2005· 113 citedOpen Access
The systemic inflammatory response syndrome
Best Practice & Research Clinical Anaesthesiology·2004· 95 cited
Bedeutung der angeborenen Immunantwort in der Sepsis
Der Anaesthesist·2004· 24 citedOpen Access
Identification, Cloning and Characterization of Novel DAP12-associated Receptors Expressed on Myeloid Cells
2002
Identifizierung, Klonierung und Charakterisierung von neuen DAP12-assoziierten Rezeptoren exprimiert von myeloiden Zellen
2002
Cutting Edge: Activation of NK Cell-Mediated Cytotoxicity by a SAP-Independent Receptor of the CD2 Family
The Journal of Immunology·2001· 196 citedOpen Access
A Dap12-Mediated Pathway Regulates Expression of Cc Chemokine Receptor 7 and Maturation of Human Dendritic Cells
The Journal of Experimental Medicine·2001· 460 citedOpen Access
TREM-1 amplifies inflammation and is a crucial mediator of septic shock
Nature·2001· 1.1k cited
Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity
European Journal of Immunology·2000· 164 citedOpen Access
Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells.
PubMed·2000· 201 cited
Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes
The Journal of Immunology·2000· 1.3k cited
Critical role for mitochondria in B cell receptor-mediated apoptosis
European Journal of Immunology·2000· 3 citedOpen Access
Critical role for mitochondria in B cell receptor‐mediated apoptosis
European Journal of Immunology·2000· 61 cited

Frequent Co-authors

Marco Colonna(6), Markus A. Weigand(4), Marina Cella(3), Henning Walczak(3), Peter H. Krammer(3), Stefan Hofer(3), Mirjam Schenk(2), Christoph Mueller(2), Helen L. Grierson(2), Jeffrey I. Cohen(2), Christian Bopp(2), Angelika Bierhaus(2), Peter P. Nawroth(2), Eike Martin(2), Christian Hörner(2), E. Martin(2), M. A. Weigand(2), Jes Dietrich(1), Fabio Facchetti(1), Cristina Hernández-Munaín(1)