Kazuo Fushimi

Northwestern University — United States

Medicine · Health Sciences

21h-index2.8kcitations42works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(9), RNA Research and Splicing(9), Amyotrophic Lateral Sclerosis Research(8), RNA and protein synthesis mechanisms(6), Cancer Research and Treatments(5)

Publications42 total

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
PLoS Genetics·2019· 272 citedOpen Access
FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models
Proceedings of the National Academy of Sciences·2018· 113 citedOpen Access
PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration
Human Molecular Genetics·2016· 43 citedOpen Access
FUS Interacts with HSP60 to Promote Mitochondrial Damage
PLoS Genetics·2015· 190 citedOpen Access
<scp>USP</scp>33 mediates <scp>S</scp>lit‐<scp>R</scp>obo signaling in inhibiting colorectal cancer cell migration
International Journal of Cancer·2014· 66 citedOpen Access
An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution
Human Molecular Genetics·2014· 54 citedOpen Access
Alternative Pre-mRNA Splicing, Cell Death, and Cancer
Cancer treatment and research·2013· 3 cited
PSF Suppresses Tau Exon 10 Inclusion by Interacting with a Stem-Loop Structure Downstream of Exon 10
Journal of Molecular Neuroscience·2011· 47 citedOpen Access
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
Nature Structural & Molecular Biology·2011· 307 citedOpen Access
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration
Protein & Cell·2011· 95 citedOpen Access
RNA Helicase p68 (DDX5) Regulates <i>tau</i> Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5′ Splice Site
Molecular and Cellular Biology·2011· 125 citedOpen Access
Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy
Protein & Cell·2011· 112 citedOpen Access
A <i>Drosophila</i> model for TDP-43 proteinopathy
Proceedings of the National Academy of Sciences·2010· 267 citedOpen Access
Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5
Proceedings of the National Academy of Sciences·2008· 142 citedOpen Access
Polypyrimidine Tract-binding Protein (PTB) Differentially Affects Malignancy in a Cell Line-dependent Manner
Journal of Biological Chemistry·2008· 55 citedOpen Access
An Intronic Signal for Alternative Splicing in the Human Genome
PLoS ONE·2007· 19 citedOpen Access
An Intronic Signal for Alternative Splicing in the Human
2007
Pre-mRNA splicing and retinitis pigmentosa.
PubMed·2006· 124 cited
NSSRs/TASRs/SRp38s function as splicing modulators via binding to pre‐mRNAs
Genes to Cells·2005· 10 citedOpen Access
Prediction of tertiary structure of NSSRs’ RNA recognition motif and the RNA binding activity
Science and Technology of Advanced Materials·2005· 2 citedOpen Access
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Frequent Co-authors

Jane Y. Wu(18), Masayoshi Namba(13), Koichiro Mihara(11), Xiaoping Chen(8), Li Zhu(8), Jianghong Liu(8), Masahiro Miyazaki(7), Amar N. Kar(6), Payal Ray(6), Mengxue Yang(6), Jianwen Deng(6), Toshiya Tsuji(6), Eileen H. Bigio(5), Tadashi Kondo(5), Yanbo Chen(4), Marsel Mesulam(4), Ryuichiro Ohashi(4), Tohru Ohe(3), Xiaohong Zhou(3), Elizabeth J. Rao(3)