Kunitada Shimotohno

National Center for Global Health and Medicine — Japan

Medicine · Health Sciences

81h-index27.3kcitations413works2.02yr avg
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Research Topics

Hepatitis C virus research(200), Hepatitis B Virus Studies(144), T-cell and Retrovirus Studies(81), Animal Disease Management and Epidemiology(69), Liver Disease Diagnosis and Treatment(63)

Publications413 total

A synonymous mutation in the preS2 region enhances production of infectious hepatitis B virus
Virology·2025· 1 citedOpen Access
A novel synthetic bile acid derivative inhibits hepatitis B virus infection at entry step by interfering with the oligomerization of sodium taurocholate co-transporting polypeptide
Antiviral Research·2025Open Access
Identification of glycogen synthase kinase 3alpha/beta as a host factor required for HBV transcription using high-throughput screening
Hepatology·2025· 4 citedOpen Access
MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX
Frontiers in Microbiology·2025· 2 citedOpen Access
Antiviral effect of peptoids on hepatitis B virus infection in cell culture
Antiviral Research·2024· 5 citedOpen Access
Unique Strongly Alkaline Electrolyzed Water as a Sustainable Countermeasure Against COVID-19 and Future Pandemics
Integrated science·2024
N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx
International Journal of Molecular Sciences·2023· 13 citedOpen Access
A Novel Algorithm for the Personalized Assessment of 5-Year Risk of Hepatocellular Carcinoma after Eradication of Hepatitis C Virus Infection
SSRN Electronic Journal·2023Open Access
Identification of neutralizing epitopes in the preS2 domain of the hepatitis B virus
Virus Research·2022· 6 citedOpen Access
Pegylated interferon therapy-related microRNA-6126 downregulates sodium taurocholate cotransporting polypeptide expression in hepatocytes
Gene·2022· 2 cited
Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen
Nature Communications·2022· 26 citedOpen Access
Ubiquitination of SARS-CoV-2 NSP6 and ORF7a Facilitates NF-κB Activation
mBio·2022· 50 citedOpen Access
The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro
PLoS Pathogens·2022· 20 citedOpen Access
Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteins
Nature Communications·2022· 76 citedOpen Access
Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection
Journal of Virology·2022· 21 citedOpen Access
HERC5 E3 ligase mediates ISGylation of hepatitis B virus X protein to promote viral replication
Journal of General Virology·2021· 9 cited
Angiotensin–Converting Enzyme (ACE) 1 Gene Polymorphism and Phenotypic Expression of COVID-19 Symptoms
Genes·2021· 36 citedOpen Access
The kinesin KIF4 mediates HBV/HDV entry through regulation of surface NTCP localization and can be targeted by RXR agonists <i>in vitro</i>
2021· 1 citedOpen Access
Strong alkaline electrolyzed water efficiently inactivates SARS-CoV-2, other viruses, and Gram-negative bacteria
Biochemical and Biophysical Research Communications·2021· 17 citedOpen Access
MafF Is an Antiviral Host Factor That Suppresses Transcription from Hepatitis B Virus Core Promoter
Journal of Virology·2021· 20 citedOpen Access
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Frequent Co-authors

Makoto Hijikata(23), Nobuyuki Kato(13), Yuko Ootsuyama(8), Koichi Watashi(6), Takayuki Hishiki(5), Yusuke Miyanari(4), Yoshiki Murakami(4), Tsutomu Chiba(4), Yasunori Tanji(4), Torahiko Tanaka(4), Takaji Wakita(3), Shogo Ohkoshi(3), Hiroto Mizushima(3), Toshitake Tanaka(3), Kôichi Kimura(3), Hitomi Sekiya(3), Masanori Nakagawa(3), Hiroyuki Marusawa(3), Toshinobu KANEKO(3), Shinya Satoh(3)