Ronald A. Siegel

University of Minnesota — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index7.3kcitations241works3.12yr avg
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Research Topics

Hydrogels: synthesis, properties, applications(64), Drug Solubulity and Delivery Systems(28), Advanced Drug Delivery Systems(26), Microfluidic and Capillary Electrophoresis Applications(25), Surfactants and Colloidal Systems(19)

Publications241 total

Progress towards a prodrug/enzyme intranasal delivery system for rapid prevention/reversal of seizure emergency
Journal of Controlled Release·2025
Experiments and finite element simulations pertinent to hydrogel debonding from a solid substrate
Polymer·2025· 1 cited
Artificial gut Simulator. A scheme to predict intestinal and plasma concentration–time profiles of a weakly basic BCS-II drug, dipyridamole
European Journal of Pharmaceutics and Biopharmaceutics·2025· 2 cited
Impact of solid content on the bulk properties of lyophilized powders
International Journal of Pharmaceutics·2024· 5 cited
Efficient development of high drug loaded posaconazole tablets enabled by amorphous solid dispersion
RSC Pharmaceutics·2024· 4 citedOpen Access
Optimal continuous administration of drugs exhibiting tolerance: A modeling study for linear one compartment pharmacokinetics
Computers & Chemical Engineering·2024
Author response for "Efficient Development of High Drug Loaded Posaconazole Tablets Enabled by Amorphous Solid Dispersion"
2024
A Numerical Scheme and Validation of the Asymptotic Energy Release Rate Formula for a 2D Gel Thin-Film Debonding Problem
SIAM Journal on Applied Mathematics·2024· 2 cited
Miscibility of amorphous solid dispersions: A rheological and solid-state NMR spectroscopy study
Journal of Pharmaceutical Sciences·2024· 3 citedOpen Access
Delaying the first nucleation event of amorphous solid dispersions above the polymer overlap concentration (c*): PVP and PVPVA in posaconazole
Journal of Pharmaceutical Sciences·2024· 9 citedOpen Access
An Artificial Gut/Absorption Simulator: Understanding the Impact of Absorption on In Vitro Dissolution, Speciation, and Precipitation of Amorphous Solid Dispersions
Molecular Pharmaceutics·2024· 3 cited
Crystallization inhibition in molecular liquids by polymers above the overlap concentration (c*): Delay of the first nucleation event
Journal of Pharmaceutical Sciences·2024· 8 cited
Notes on the Use of Kirchhoff’s Laws in Pharmacokinetics
The AAPS Journal·2023· 6 cited
Drug-Polymer Miscibility and the Overlap Concentration (C*) as Measured by Rheology: Variation of Polymer Structure
Pharmaceutical Research·2023· 9 cited
Deconvolution of Plasma Pharmacokinetics from Dynamic Heart Imaging Data Obtained by Single Positron Emission Computed Tomography/Computed Tomography Imaging
Journal of Pharmacology and Experimental Therapeutics·2023· 1 citedOpen Access
Predetermination of burst times of elastoplastic osmotic capsules
Journal of Controlled Release·2023· 1 cited
Gels: Energetics, Singularities, and Cavitation
Journal of Elasticity·2023· 1 cited
Deconvolution of plasma pharmacokinetics from dynamic heart imaging data obtained by SPECT/CT imaging
2022· 1 citedOpen Access
Gels: Energetics, Singularities and Cavitation
Research Square (Research Square)·2022· 1 citedOpen Access
An Artificial Gut/Absorption Simulator: Simultaneous Evaluation of Desupersaturation and Absorption from Ketoconazole Supersaturated Solutions
Journal of Pharmaceutical Sciences·2022· 3 cited
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Frequent Co-authors

Bruce A. Firestone(6), Babak Ziaie(5), Antonio Baldi(4), Róbert Langer(4), Eric Nuxoll(4), Yuandong Gu(3), Ahmad Hivechi(3), S. Hajir Bahrami(3), Ming Lei(3), Juergen Siepmann(2), Michael J. Rathbone(2), Sidhartha S. Jena(2), Volker Schellenberger(2), James C. Cloyd(2), C. Anthony Hunt(2), Gauri P. Misra(2), Siddharthya Mujumdar(2), M. Falamarzian(1), Bret C. Moxley(1), Jonathan Carlson(1)