Luca Lazzari

Vita-Salute San Raffaele University — Italy

Medicine · Health Sciences

22h-index3.4kcitations144works1.72yr avg
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Research Topics

Colorectal Cancer Treatments and Studies(68), Cancer Genomics and Diagnostics(42), Genetic factors in colorectal cancer(27), Lung Cancer Treatments and Mutations(22), Radiomics and Machine Learning in Medical Imaging(18)

Publications144 total

Total neoadjuvant therapy followed by non-operative management or surgery in stage II–III rectal cancer (NO-CUT): a multicentre, single-arm, phase 2 trial
The Lancet Oncology·2025· 5 cited
34P Histology meets AI: Decoding minimal residual disease risk (MRDR) and stromal signatures in the colon cancer (CC) PEGASUS trial
ESMO Real World Data and Digital Oncology·2025Open Access
The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy in Metastatic Colorectal Cancer
Cancer Discovery·2025· 1 citedOpen Access
723O Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: Final results of the PEGASUS trial
Annals of Oncology·2025· 2 cited
Early-Onset Colorectal Cancers Exhibit Distinctive Placental-Like Features
2025Open Access
AI-Driven Pathomics for Predicting Chemotherapy Response in Metastatic Colorectal Cancer: A Transfer Learning Approach with Attention-Based Multiple Instance Learning
2025
Stain normalization matters: impact on feature relevance and classifier performance in mCRC therapy response prediction
2025
114P Radiologist concordance and pathology correlation in non metastatic colon cancer (NMCC) staging
Annals of Oncology·2025
342 | ANTI‐CD19 CHIMERIC ANTIGEN RECEPTOR T‐CELLS THERAPY IS EFFECTIVE IN SECONDARY CNS LYMPHOMA REFRACTORY TO HIGH‐DOSE METHOTREXATE‐BASED CHEMOTHERAPY
Hematological Oncology·2025Open Access
A precision medicine trial leveraging tissue and blood-based tumor genomics to optimize treatment in resected stage III and high-risk stage II colon cancer (CC) patients (pts): The SAGITTARIUS trial.
Journal of Clinical Oncology·2025· 2 cited
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer
Science Translational Medicine·2025· 4 cited
Clinical utility and future perspectives of liquid biopsy in colorectal cancer
Communications Medicine·2025· 7 citedOpen Access
Abstract 2370: Microbiome alterations of colorectal cancer according to age of onset, stage, anatomic location, and mismatch repair deficiency
Cancer Research·2025
Selective Translation Under Heat Shock: Integrating HSP70 mRNA Regulation with Cellular Stress Responses in Yeast and Mammals
Molecular Biology of the Cell·2025· 6 cited
A Comparative Study of Methyl-BEAMing and Droplet Digital PCR for MGMT Gene Promoter Hypermethylation Detection
Diagnostics·2024· 1 citedOpen Access
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition
npj Precision Oncology·2024· 3 citedOpen Access
63O Transcriptional features of stage IIT4N0/III colon cancer associated with residual disease and ctDNA status after surgery in the PEGASUS trial
Annals of Oncology·2024
Development And Validation Of An AI-Based Pathomics Biomarker To Predict Response To First-Line Treatment In Metastatic Colorectal Cancers
Proceedings of the World Congress on New Technologies·2024· 1 citedOpen Access
26P Response in patient-derived models recapitulates circulating tumor DNA clearance of matched colon cancer patients after adjuvant treatment in the PEGASUS trial
Annals of Oncology·2024Open Access
Abstract 900: Development and validation of an artificial-intelligence-based pathomics biomarker to predict resistance to first-line treatment in metastatic colorectal cancer
Cancer Research·2024
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Frequent Co-authors

Alberto Bardelli(34), Salvatore Siena(30), Federica Di Nicolantonio(26), Andrea Sartore‐Bianchi(26), Silvia Marsoni(23), Livio Trusolino(16), Mariangela Russo(15), Giorgio Corti(15), Giovanni Crisafulli(15), Giulia Siravegna(14), Sabrina Arena(13), Emanuele Valtorta(12), Benedetta Mussolin(11), Alessio Amatu(11), Andrea Bertotti(11), Filippo Pietrantonio(10), Gianluca Mauri(10), Paolo Luraghi(9), Emanuela Bonoldi(9), Alice Bartolini(8)