Alessio Ugolini

The Wistar Institute — United States

Medicine · Health Sciences

11h-index822citations50works20.52yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(28), Immunotherapy and Immune Responses(24), CAR-T cell therapy research(22), Immune cells in cancer(13), Cancer, Hypoxia, and Metabolism(5)

Publications50 total

Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma 3605
The Journal of Immunology·2025Open Access
Hypoxia-driven histone lactylation reprograms immunosuppressive neutrophils within the glioblastoma tumor micro-environment 2119
The Journal of Immunology·2025Open Access
Data from Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation
2025Open Access
Supplementary Tables S1-S4 from Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation
2025Open Access
Figure S1-S10 from Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation
2025Open Access
Excel Table 1 from Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation
2025Open Access
ABS0179 UNDERSTANDING CAR-TREG PERSISTENCE AND EXPANSION PROTOCOLS OPTIMIZATION
Annals of the Rheumatic Diseases·2025Open Access
Abstract 6142: Functional reprogramming of neutrophils in the tumor microenvironment
Cancer Research·2025
Protocol to study the genomic profile of histone lactylation with CUT&RUN assay in tumor-associated macrophages
STAR Protocols·2025Open Access
Correction: Myeloid activation clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer
The Journal of Experimental Medicine·2025Open Access
Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation
Cancer Discovery·2025· 38 citedOpen Access
Exploring Genomic Biomarkers for Pembrolizumab Response: A Real-World Approach and Patient Similarity Network Analysis Reveal DNA Response and Repair Gene Mutations as a Signature
Cancers·2024· 2 citedOpen Access
Myeloid activation clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer
The Journal of Experimental Medicine·2024· 10 citedOpen Access
Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer
2024· 1 citedOpen Access
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
Immunity·2024· 203 citedOpen Access
Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus
Nature Communications·2024· 74 citedOpen Access
POS1432 CAR-TREGS FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Annals of the Rheumatic Diseases·2023Open Access
Supplementary Figure from Circulating CD137<sup>+</sup> T Cells Correlate with Improved Response to Anti-PD1 Immunotherapy in Patients with Cancer
2023Open Access
Supplementary Figure from Circulating CD137<sup>+</sup> T Cells Correlate with Improved Response to Anti-PD1 Immunotherapy in Patients with Cancer
2023Open Access
Supplementary Table from Circulating CD137<sup>+</sup> T Cells Correlate with Improved Response to Anti-PD1 Immunotherapy in Patients with Cancer
2023Open Access
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Frequent Co-authors

Marianna Nuti(34), Aurelia Rughetti(33), Fabio Scirocchi(29), Andrea Botticelli(26), Paolo Marchetti(25), Ilaria Grazia Zizzari(24), Chiara Napoletano(22), Lidia Strigari(21), Alessandra Di Filippo(20), Alain Gelibter(20), Angelina Pernazza(19), Emma Rullo(19), Maria Gemma Pignataro(19), Francesca Romana Di Pietro(19), Ernesto Rossi(19), Giovanni Schinzari(19), Giulia d’Amati(19), Filippo Veglia(15), Alessandra De Leo(11), Xiaoqing Yu(6)