Karen H. Vousden

The Francis Crick Institute — United Kingdom

Medicine · Health Sciences

120h-index71.4kcitations377works31.22yr avg
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Research Topics

Cancer-related Molecular Pathways(198), Ubiquitin and proteasome pathways(71), Cancer, Hypoxia, and Metabolism(67), Cancer Research and Treatments(60), Epigenetics and DNA Methylation(52)

Publications370 total

In conversation with Karen Vousden
FEBS Journal·2026
Sensing of extracellular <scp>l</scp> -proline availability by the integrated stress response determines the outcome of cell competition
Science Advances·2025· 1 citedOpen Access
p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
JHEP Reports·2025· 2 citedOpen Access
Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment
Proceedings of the National Academy of Sciences·2024· 5 citedOpen Access
Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition
2024· 1 citedOpen Access
The pro-oncogenic noncanonical activity of a RAS•GTP:RanGAP1 complex facilitates nuclear protein export
Nature Cancer·2024· 9 citedOpen Access
Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities
Cold Spring Harbor Perspectives in Medicine·2024· 2 cited
Obesity, white adipose tissue and cancer
FEBS Journal·2024· 15 citedOpen Access
Cancer Metabolism: Aspirations for the Coming Decade
Cold Spring Harbor Perspectives in Medicine·2024· 4 citedOpen Access
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
Nature Communications·2024· 38 citedOpen Access
p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
2024Open Access
Cycling back to folate metabolism in cancer
Nature Cancer·2024· 36 citedOpen Access
Abstract 2089: A pro-oncogenic RAS-GTP:RAN-GAP complex facilitates nuclear protein export and has clinical implications
Cancer Research·2024
Embracing cancer complexity: Hallmarks of systemic disease
Cell·2024· 384 citedOpen Access
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma
Journal of Clinical Investigation·2024· 1 citedOpen Access
Recovering from the stress of the COVID-19 pandemic
Molecular Cell·2024· 1 citedOpen Access
Phenotypic profiling of solute carriers characterizes serine transport in cancer
Nature Metabolism·2023· 39 citedOpen Access
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
Nature Genetics·2023· 76 citedOpen Access
A century of the Warburg effect
Nature Metabolism·2023· 102 cited
Loss of attachment promotes proline accumulation and excretion in cancer cells
Science Advances·2023· 20 citedOpen Access
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Frequent Co-authors

Oliver D.K. Maddocks(8), Robert L. Ludwig(6), Eyal Gottlieb(4), Patricia Müller(4), Eric C. Cheung(4), Christiaan F. Labuschagne(4), John Tidy(4), Michael H.G. Kubbutat(3), Jane P. Jensen(3), Allan M. Weissman(3), Andrew C. Phillips(3), Gerry Melino(3), Tim Crook(3), Margaret Ashcroft(3), Gérard I. Evan(2), Karim Bensaad(2), Flore Kruiswijk(2), Celia R. Berkers(2), Liang Zheng(2), Karen Blyth(2)