Lindsey Van Haute

University of Cambridge — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.7kcitations51works2.32yr avg
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Research Topics

Mitochondrial Function and Pathology(20), RNA and protein synthesis mechanisms(19), RNA modifications and cancer(17), CRISPR and Genetic Engineering(11), Pluripotent Stem Cells Research(7)

Publications51 total

Biallelic <i>NSUN3</i> Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder
Investigative Ophthalmology & Visual Science·2025· 3 citedOpen Access
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture
EMBO Molecular Medicine·2025· 6 citedOpen Access
Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery
2025Open Access
Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery
2025Open Access
Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery
2024Open Access
Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease
EMBO Molecular Medicine·2024· 3 citedOpen Access
172P FUS protein expression in the myopathology of 5q-associated spinal muscular atrophy type 3
Neuromuscular Disorders·2024
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis
RNA Biology·2024· 6 citedOpen Access
Transcriptome Sequencing Reveals the Mechanism behind Chemically Induced Oral Mucositis in a 3D Cell Culture Model
International Journal of Molecular Sciences·2023· 2 citedOpen Access
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease
Nature Communications·2023· 28 citedOpen Access
A library of base editors for the precise ablation of all protein-coding genes in the mouse mitochondrial genome
Nature Biomedical Engineering·2022· 56 citedOpen Access
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
Nature Communications·2022· 41 citedOpen Access
In vivo mitochondrial base editing via adeno-associated viral delivery to mouse post-mitotic tissue
Nature Communications·2022· 80 citedOpen Access
The FASTK family proteins fine-tune mitochondrial RNA processing
PLoS Genetics·2021· 40 citedOpen Access
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
2021· 5 citedOpen Access
YbeY is required for ribosome small subunit assembly and tRNA processing in human mitochondria
Nucleic Acids Research·2021· 15 citedOpen Access
The FASTK family proteins fine-tune mitochondrial RNA processing.
SHILAP Revista de lepidopterología·2021Open Access
Quantitative density gradient analysis by mass spectrometry (qDGMS) and complexome profiling analysis (ComPrAn) R package for the study of macromolecular complexes
Biochimica et Biophysica Acta (BBA) - Bioenergetics·2021· 28 citedOpen Access
Detection of 5-formylcytosine in Mitochondrial Transcriptome
Methods in molecular biology·2020· 12 cited
ComPrAn – R package for analysis of complexome profiling experiments
Faculty of 1000 Research Ltd·2020Open Access
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Frequent Co-authors

Michal Minczuk(35), Christopher A. Powell(17), Pedro Rebelo‐Guiomar(14), Karen Sermon(9), Joanna Rorbach(8), Christian D. Mutti(8), Aaron R. D’Souza(7), Claudia Spits(6), Pedro Silva-Pinheiro(6), Keira Turner(6), Sara Seneca(5), Payam A. Gammage(5), Martine De Rycke(5), Sarah F. Pearce(5), Caterina Garone(4), Andrew E. Firth(4), P. Nash(4), Petra Páleníková(4), Mieke Geens(4), Joél Smet(3)