Shannon Rivera

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index277citations22works2.52yr avg
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Research Topics

Protein purification and stability(11), Viral Infectious Diseases and Gene Expression in Insects(7), Hemoglobin structure and function(7), Advanced Proteomics Techniques and Applications(5), Monoclonal and Polyclonal Antibodies Research(5)

Publications22 total

Elucidation of cell culture impacts on hydroxylysine levels in monoclonal antibodies using high‐throughput analytical quantification and media components
Biotechnology Progress·2025· 1 cited
Fragmentation of recombinant human interleukin-12 by matriptase in CHO cell culture
Journal of Biotechnology·2025· 1 cited
Turning diverse analytical data into actionable knowledge for enzymatically driven polysorbate degradation risk assessment and control in biotherapeutic protein formulations
Journal of Pharmaceutical and Biomedical Analysis Open·2025Open Access
Systematic Optimization of Activity-Based Protein Profiling for Identification of Polysorbate-Degradative Enzymes in Biotherapeutic Drug Substance down to 10 ppb
Journal of the American Society for Mass Spectrometry·2024· 2 cited
Development of a multiplexing method for the quantification of “high-risk” host cell lipases in biotherapeutics by Luminex
Analytica Chimica Acta·2024· 3 cited
Systematic Optimization of Activity-Based Protein Profiling for Identification of Polysorbate-Degradative Enzymes in Biotherapeutic Drug Substance Down to 10 ppb
2024· 1 citedOpen Access
Heme pocket hydrogen bonding residue interactions within the Pectobacterium Diguanylate cyclase-containing globin coupled sensor: A resonance Raman study
Journal of Inorganic Biochemistry·2024· 4 cited
diaPASEF Enables High-Throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development
Analytical Chemistry·2024· 13 cited
Heme pocket modulates protein conformation and diguanylate cyclase activity of a tetrameric globin coupled sensor
Journal of Inorganic Biochemistry·2024· 3 citedOpen Access
diaPASEF Enables High-throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development
2024Open Access
Development of a Multiplexing Method for the Quantification of “High-Risk” Host Cell Lipases in Biotherapeutics by Luminex
SSRN Electronic Journal·2024Open Access
Cationic polymer precipitation for enhanced impurity removal in downstream processing
Biotechnology and Bioengineering·2023· 6 cited
Improvements on sample preparation and peptide separation for reduced peptide mapping based multi-attribute method analysis of therapeutic monoclonal antibodies using lysyl endopeptidase digestion
Journal of Chromatography A·2022· 20 cited
Improvements on Sample Preparation and Peptide Separation for Reduced Peptide Mapping Based Multi-Attribute Method analysis of Therapeutic Monoclonal Antibodies Using Lys-C Digestion
2022· 1 citedOpen Access
Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling
Analytical Chemistry·2021· 60 cited
Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors
Inorganic Chemistry·2018· 25 cited
Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen <i>Pectobacterium carotovorum</i>
ACS Chemical Biology·2017· 20 cited
Mechanism and Role of Globin-Coupled Sensor Signalling
Advances in microbial physiology/Advances in Microbial Physiology·2017· 37 cited
Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example
BIO-PROTOCOL·2017· 2 citedOpen Access
Oxygen and Bis(3′,5′)-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Biochemistry·2016· 25 cited
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Frequent Co-authors

Emily E. Weinert(9), Xuanwen Li(8), Jonathan Welch(4), Taku Tsukidate(4), Alyssa Q. Stiving(4), Simon Letarte(3), Douglas D. Richardson(3), Paul G. Young(3), Justin L. Burns(3), Anita P. Liu(3), Divya Chandra(2), Rong‐Sheng Yang(2), Alex Dow(2), Gregory E. Vansuch(2), Baibhav Rawal(2), Ansuman Sahoo(2), Sri Ranganayaki Madabhushi(2), Yilin Liu(2), J.D. Osko(2), Fengqiang Wang(2)