Joseph R. Spangler

United States Naval Research Laboratory — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index412citations23works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(6), Probiotics and Fermented Foods(5), Bacterial Genetics and Biotechnology(4), CRISPR and Genetic Engineering(4), Advanced biosensing and bioanalysis techniques(3)

Publications23 total

<i>In</i> <i>Vitro</i> Fermentation Evaluation of Engineered Sense and Respond Probiotics in Polymicrobial Communities
ACS Biomaterials Science & Engineering·2023· 2 cited
Different Strategies Affect Enzyme Packaging into Bacterial Outer Membrane Vesicles
Bioengineering·2023· 10 citedOpen Access
Machine learning for design of degenerate Cas13a crRNAs using lassa virus as a model of highly variable RNA target
Scientific Reports·2023· 7 citedOpen Access
Factors limiting the sensitivity of DNA-conjugated quantum dot molecular beacons
2023· 1 cited
Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas disease
Memórias do Instituto Oswaldo Cruz·2023· 4 citedOpen Access
Passivating quantum dots against histag-displaying enzymes using blocking peptides: salient considerations for self-assembling quantum dot biosensors
Sensors & Diagnostics·2023· 10 citedOpen Access
Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas disease
Figshare·2023Open Access
Quantum Dot-Based Molecular Beacons for Quantitative Detection of Nucleic Acids with CRISPR/Cas(N) Nucleases
ACS Nano·2022· 72 cited
Large scale screening of CRISPR guide RNAs using an optimized high throughput robotics system
Scientific Reports·2022· 12 citedOpen Access
Promoter Identification and Optimization for the Response of <i>Lactobacillus plantarum</i> WCFS1 to the Gram-Negative Pathogen-Associated Molecule <i>N</i>-3-Oxododecanoyl Homoserine Lactone
ACS Biomaterials Science & Engineering·2022· 4 cited
Self-assembled nanoparticle-enzyme aggregates enhance functional protein production in pure transcription-translation systems
PLoS ONE·2022· 13 citedOpen Access
Packaging of Diisopropyl Fluorophosphatase (DFPase) in Bacterial Outer Membrane Vesicles Protects Its Activity at Extreme Temperature
ACS Biomaterials Science & Engineering·2022· 6 cited
Extracellular vesicle production in Gram‐positive bacteria
Microbial Biotechnology·2021· 13 citedOpen Access
In Situ Self‐Assembly of Quantum Dots at the Plasma Membrane Mediates Energy Transfer‐Based Activation of Channelrhodopsin (Part. Part. Syst. Charact. 7/2021)
Particle & Particle Systems Characterization·2021Open Access
In Situ Self‐Assembly of Quantum Dots at the Plasma Membrane Mediates Energy Transfer‐Based Activation of Channelrhodopsin
Particle & Particle Systems Characterization·2021· 1 cited
Harnessing the Potential of <i>Lactobacillus</i> Species for Therapeutic Delivery at the lumenal-mucosal Interface
Future Science OA·2021· 6 citedOpen Access
The <i>E. coli</i> NudL enzyme is a Nudix hydrolase that cleaves CoA and its derivatives
2020· 3 citedOpen Access
Exploiting the Feedstock Flexibility of the Emergent Synthetic Biology Chassis Vibrio natriegens for Engineered Natural Product Production
Marine Drugs·2019· 62 citedOpen Access
Response of Lactobacillus plantarum WCFS1 to the Gram-Negative Pathogen-Associated Quorum Sensing Molecule N-3-Oxododecanoyl Homoserine Lactone
Frontiers in Microbiology·2019· 28 citedOpen Access
Broad range shuttle vector construction and promoter evaluation for the use of Lactobacillus plantarum WCFS1 as a microbial engineering platform
Synthetic Biology·2019· 34 citedOpen Access
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Frequent Co-authors

Scott A. Walper(13), Igor L. Medintz(7), Meghna Thakur(6), David A. Stenger(5), Scott N. Dean(5), Eunkeu Oh(5), Kimihiro Susumu(4), Faqing Huang(3), Christopher M. Green(3), Sebastián A. Dı́az(3), Gregory A. Ellis(3), Julie Caruana(2), Tomasz A. Łęski(2), Zachary Schultzhaus(2), Kimihiro Susumu(2), María Elisa Vázquez(2), Andrea C. Mesías(2), Leonardo Acuña(2), Brenda A. Zabala(2), Cecilia Parodi(2)