Axel Pagenstecher

Medicine · Health Sciences

43h-index5.7kcitations150works6.72yr avg
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Research Topics

Glioma Diagnosis and Treatment(15), Protease and Inhibitor Mechanisms(14), Virology and Viral Diseases(12), Peptidase Inhibition and Analysis(12), Neuroinflammation and Neurodegeneration Mechanisms(11)

Publications150 total

p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo
Cell Reports·2025Open Access
Chick chorioallantoic membrane model as a preclinical platform for cryoablation studies
European Radiology Experimental·2025· 1 citedOpen Access
The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
Immunity·2024· 27 citedOpen Access
Status epilepticus in patients with brain tumors and metastases: A multicenter cohort study of 208 patients and literature review
Neurological Research and Practice·2024· 7 citedOpen Access
A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1
Cells·2024· 4 citedOpen Access
Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates
2024· 1 citedOpen Access
Immunoproteasome deficiency results in age-dependent development of epilepsy
Brain Communications·2023· 7 citedOpen Access
Correlation of MR-Based Metabolomics and Molecular Profiling in the Tumor Microenvironment of Temozolomide-Treated Orthotopic GL261 Glioblastoma in Mice
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson’s disease
Nature Communications·2023· 22 citedOpen Access
Feasibility of the chick chorioallantoic membrane model for preclinical studies on tumor radiofrequency ablation
European Radiology Experimental·2023· 5 citedOpen Access
Immunoproteasome deficiency results in accelerated brain aging and epilepsy
2023Open Access
Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis
Cancer Cell International·2023· 12 citedOpen Access
Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis
2022Open Access
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase
Molecular Cancer·2022· 18 citedOpen Access
Electron Microscopy of Cells Grown on Polyacrylamide Hydrogels
Current Protocols·2022Open Access
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity
Cell Death and Differentiation·2022· 12 citedOpen Access
IRF4 deficiency vulnerates B cell progeny for leukemogenesis via somatically acquired <i>Jak3</i> mutations conferring IL-7 hypersensitivity
2022Open Access
Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson’s disease mice
Brain Behavior and Immunity·2022· 110 citedOpen Access
Additional file 3 of Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase
Figshare·2022Open Access
Additional file 4 of Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase
Figshare·2022Open Access
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Frequent Co-authors

Iain L. Campbell(12), Anna K. Stalder(7), Carrie Kincaid(6), Benedikt Volk(6), Jürgen Hausmann(5), Peter Staeheli(5), Johannes Lutterbach(4), Ulrich Sure(3), Christoph B. Ostertag(3), Ansgar Berlis(3), Valérie C. Asensio(3), Wiebke Hallensleben(3), Ghislain Opdenakker(3), Heymut Omran(2), Alexander Visekruna(2), Jörg W. Bartsch(2), Ursula Keber(2), Monica J. Carson(2), Linfang Wang(2), Emmanouil Fokas(2)