Steven B. Marston

Imperial College London — United Kingdom

Medicine · Health Sciences

60h-index10.4kcitations331works1.62yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(236), Cardiovascular Effects of Exercise(97), Muscle Physiology and Disorders(96), Cellular Mechanics and Interactions(34), Viral Infections and Immunology Research(28)

Publications322 total

Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy
Science Translational Medicine·2025· 6 cited
Review for "Myopathy-linked mutations in <i>TPM2</i> and their impact on troponin-mediated regulation of actomyosin contractility"
2025
5,7-Dimethoxychroman-3-yl 4-methoxybenzoate Has a Unique Effect upon the Modulation of Mutant Cardiac Muscle Thin Filament Function and Dynamics due to Phosphorylation of Troponin I
ACS Pharmacology & Translational Science·2025· 1 citedOpen Access
Review for "Myopathy-linked mutations in <i>TPM2</i> and their impact on troponin-mediated regulation of actomyosin contractility"
2025
Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro, in vivo, and in silico
Frontiers in Physiology·2024· 3 citedOpen Access
Nutraceuticals Silybin B, resveratrol and epigallocatechin-3 gallate (EGCG) bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations <i>in vitro, in vivo</i> , and <i>in silico</i>
2024Open Access
Complex architecture of cardiac muscle thick filaments revealed
Trends in Pharmacological Sciences·2024· 1 citedOpen Access
Modulation of Structure and Dynamics of Cardiac Troponin by Phosphorylation and Mutations Revealed by Molecular Dynamics Simulations
The Journal of Physical Chemistry B·2023· 7 citedOpen Access
Suppression of lusitropy as a disease mechanism in cardiomyopathies
Frontiers in Cardiovascular Medicine·2023· 20 citedOpen Access
Modulation of structure and dynamics of cardiac troponin by phosphorylation and mutations revealed by molecular dynamics simulations
2022· 2 citedOpen Access
Recent studies of the molecular mechanism of lusitropy due to phosphorylation of cardiac troponin I by protein kinase A
Journal of Muscle Research and Cell Motility·2022· 11 citedOpen Access
Modulation of cardiac thin filament structure by phosphorylated troponin-I analyzed by protein-protein docking and molecular dynamics simulation
Archives of Biochemistry and Biophysics·2022· 19 citedOpen Access
N-Terminal domains of cardiac troponin-I modulate thin filament structure
Biophysical Journal·2022
Force Measurements From Myofibril to Filament
Frontiers in Physiology·2022· 6 citedOpen Access
Session 2. Cardiac/smooth muscle ultrastructure and regulation
Acta Biochimica Polonica·2021Open Access
Richard Tregear, Co-founder of the Journal of Muscle Research and Cell Motility
Journal of Muscle Research and Cell Motility·2021Open Access
Small Molecules Acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases
International Journal of Molecular Sciences·2020· 53 citedOpen Access
Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation
Cardiovascular Research·2020· 36 citedOpen Access
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics
Proceedings of the National Academy of Sciences·2020· 101 citedOpen Access
Donor hearts in the Sydney Heart Bank: reliable control but is it ‘normal’ heart?
Biophysical Reviews·2020· 2 citedOpen Access
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Frequent Co-authors

Charles Redwood(11), Hugh Watkins(8), O’Neal Copeland(6), Andrew E. Messer(6), Adam Jacques(5), William J. McKenna(4), Adam Knott(4), Cristobal G. dos Remedios(4), Wu Bing(4), Victor Tsang(3), Christopher W. J. Smith(3), Nikolai B. Gusev(3), William Lehman(3), M Mirza(3), Paul Robinson(3), R. T. Tregear(3), Kristen L. Nowak(3), Mohammed El‐Mezgueldi(3), Ian Purcell(3), Giovanna Esposito(3)