Patrick Sung

The University of Texas Health Science Center at San Antonio — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

88h-index27.9kcitations388works6.82yr avg
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Research Topics

DNA Repair Mechanisms(320), CRISPR and Genetic Engineering(136), Carcinogens and Genotoxicity Assessment(71), DNA and Nucleic Acid Chemistry(69), PARP inhibition in cancer therapy(59)

Publications387 total

Author Correction: Structural insights into BCDX2 complex function in homologous recombination
Nature·2026Open Access
Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Anti-tumor Immunity
Cancer Research·2025
Cryo-EM structures reveal the molecular mechanism of SUMO E1–E2 thioester transfer
Nature Structural & Molecular Biology·2025· 3 citedOpen Access
Phosphoregulation of RAD51AP1 function in homology-directed repair
2025Open Access
Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51
Molecular Cell·2025
Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recombination and replicative functions
Nature Communications·2025· 3 citedOpen Access
Abstract P5-06-06: The Mechanistic Role of BRCA1 DNA and RAD51 Binding in DNA Double-Strand Break Repair
Clinical Cancer Research·2025
Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51
Molecular Cell·2025· 3 cited
CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade
Science·2025· 7 cited
Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation
Cell Reports·2025· 4 citedOpen Access
Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory
Nature Communications·2025· 6 citedOpen Access
Endogenous DNA damage at sites of terminated transcripts
Nature·2025· 7 citedOpen Access
Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy
EMBO Molecular Medicine·2025· 7 citedOpen Access
Deciphering the fate of replication-induced DNA double-strand breaks
Molecular Cell·2025· 2 cited
PLK1 Acts in Homologous Recombinatorial Repair and in Mitosis As Synthetically Lethal with the Fanconi Anemia/BRCA Pathway
Blood·2024· 1 citedOpen Access
Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors
Molecular Cancer·2024· 8 citedOpen Access
Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation
2024· 1 citedOpen Access
Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination
Nature·2024· 29 citedOpen Access
Correction: Dynamic interactions of the homologous pairing 2 (Hop2)–meiotic nuclear divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast
Journal of Biological Chemistry·2024Open Access
BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
Molecular Cell·2024· 42 citedOpen Access
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Frequent Co-authors

Satya Prakash(10), Louise Prakash(10), Stephen Van Komen(9), Hengyao Niu(6), Youngho Kwon(6), Hannah L. Klein(5), Kelly M. Trujillo(5), Stefán Sigurðsson(5), Lumír Krejčí(4), Michael G. Sehorn(4), Weixing Zhao(4), Peter Chi(4), Grzegorz Ira(4), Eric C. Greene(4), Wendy Bussen(4), Galina Petukhova(3), Sabrina A. Stratton(3), Lucy Lu(3), Claudia Wiese(3), Steven Raynard(3)