Karen Peynshaert

Twitter (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index2.1kcitations51works4.22yr avg
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Research Topics

Retinal Development and Disorders(21), RNA Interference and Gene Delivery(15), Retinal and Macular Surgery(14), Retinal Diseases and Treatments(11), Advanced biosensing and bioanalysis techniques(6)

Publications51 total

Photodisruption of the Inner Limiting Membrane Promotes Retinal Engraftment of Stem-Cell Derived Retinal Ganglion Cells
Investigative Ophthalmology & Visual Science·2026Open Access
Overcoming size barriers in retinal gene therapy via lipid nanoparticle-mediated delivery of full-length eys DNA
Drug Delivery and Translational Research·2026
Strategic lipid nanoparticle design dictates retinal delivery post inner limiting membrane disruption
Drug Delivery and Translational Research·2025
Advancing nanoparticle delivery studies: flow cytometry-based quantification of nanoparticle uptake and transfection in retinal tissue
Drug Delivery and Translational Research·2025· 2 citedOpen Access
Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye
Journal of Controlled Release·2025· 8 citedOpen Access
Toward successful retinal drug delivery after intravitreal injection: Current strategies to overcome the inner limiting membrane
Journal of Controlled Release·2025· 7 cited
Photodisruption of the inner limiting membrane promotes retinal engraftment of stem-cell derived retinal ganglion cells
2025· 1 citedOpen Access
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis
Journal of Controlled Release·2025· 2 cited
Less is more: Self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells
European Journal of Pharmaceutics and Biopharmaceutics·2024· 18 citedOpen Access
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
Molecular Neurodegeneration·2023· 71 citedOpen Access
Exploring light for advanced drug delivery & surgery in the eye
Macedonian Pharmaceutical Bulletin·2023Open Access
Every nano-step counts: a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy
Expert Opinion on Drug Delivery·2023· 6 citedOpen Access
Photodisruption of the Inner Limiting Membrane: Exploring ICG Loaded Nanoparticles as Photosensitizers
Pharmaceutics·2022· 20 citedOpen Access
ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery
Journal of Controlled Release·2022· 34 cited
Laser-induced nanobubbles safely ablate vitreous opacities in vivo
Nature Nanotechnology·2022· 72 citedOpen Access
Enzyme-modified nanoparticles as a possible strategy for safe and effective vitreous liquefaction
Investigative Ophthalmology & Visual Science·2021Open Access
ICG-mediated photoporation of the ILM to enhance retinal drug delivery after intravitreal injection
Investigative Ophthalmology & Visual Science·2021Open Access
Vaccinia Virus Protein B18R: Influence on mRNA Immunogenicity and Translation upon Non-Viral Delivery in Different Ocular Cell Types
Pharmaceutics·2021· 5 citedOpen Access
Ocular barriers to retinal delivery of intravitreal liposomes: Impact of vitreoretinal interface
Journal of Controlled Release·2020· 108 citedOpen Access
Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution
Experimental Eye Research·2020· 88 cited
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Frequent Co-authors

Stefaan C. De Smedt(39), Katrien Remaut(38), Kevin Braeckmans(26), Joke Devoldere(14), Félix Sauvage(9), Kaat De Clerck(8), Jo Demeester(7), Stefaan J. Soenen(6), Ranhua Xiong(5), Emma De Coster(5), Koen Raemdonck(4), Sylvie Lierman(4), Kelly Tilleman(4), Steven Weyers(4), Lies De Groef(4), Lieve Moons(4), An‐Katrien Minnaert(4), Bella B. Manshian(3), Chloë De Roo(3), Cornelis B. Lambalk(3)