Nabil G. Seidah

Montreal Clinical Research Institute — Canada

Medicine · Health Sciences

114h-index56.3kcitations907works3.52yr avg
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Research Topics

Lipoproteins and Cardiovascular Health(159), Cellular transport and secretion(132), Neuropeptides and Animal Physiology(122), Receptor Mechanisms and Signaling(118), Endoplasmic Reticulum Stress and Disease(75)

Publications904 total

Identification of a novel apoB variant in a family exhibiting hypocholesterolemia: mechanistic insights
Journal of clinical lipidology·2026
High levels of serum cholesterol increase the risk of developing vessel co‐opting tumors in colorectal cancer liver metastases
FEBS Journal·2025Open Access
Identification of a Novel apoB Variant in a Family Exhibiting Hypocholesterolemia: Mechanistic Insights
Preprints.org·2025Open Access
Abstract C059: Development of a Differentiated, Best-in-Class Oral Cbl-b Inhibitor with Robust Immune Activation and Favourable Safety for Cancer Immunotherapy
Molecular Cancer Therapeutics·2025
Proteolytic processing of the Marburg virus glycoprotein depends on Sec61β and is required for cell entry
2025Open Access
Shedding of GPP130 by PC7 and Furin: Potential Implication in Lung Cancer Progression
International Journal of Molecular Sciences·2025· 1 citedOpen Access
Immunogenicity of NSDV GP38 and the role of furin in GP38 proteolytic processing
Journal of Virology·2025Open Access
Blockade of colon cancer metastasis via single and double silencing of <i>PCSK7</i>/<i>PCSK9</i>: enhanced T cells cytotoxicity in mouse and human
Journal for ImmunoTherapy of Cancer·2025· 2 citedOpen Access
Plasma ANGPTL3, Apo CIII, leptin, and lipid levels in patients with metastatic prostate cancer.
Journal of Clinical Oncology·2025
Shedding of GPP130 by PC7 and Furin: Potential Implication in Lung Cancer Progression
Preprints.org·2025· 1 citedOpen Access
Lipid Profile, <scp>PCSK9</scp>, <scp>ANGPTL3</scp> and Lipoprotein (a) Levels in Men Diagnosed With Localized High‐Grade Prostate Cancer and Men At‐Risk of Prostate Cancer
Cancer Medicine·2025· 2 citedOpen Access
Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis
Science·2025· 31 citedOpen Access
The Biology and Clinical Implications of PCSK7
Endocrine Reviews·2024· 5 citedOpen Access
Targeting proprotein convertase subtilisin/kexin type 7 in macrophages as a therapeutic strategy to mitigate myocardial infarction-induced inflammation
BMB Reports·2024· 1 citedOpen Access
Correction: Circulating levels of PCSK9, ANGPTL3 and lp(a) in stage III breast cancers
BMC Cancer·2024Open Access
PCSK9 in metabolism and diseases
Metabolism·2024· 28 citedOpen Access
Shedding of GPP130 by PC7 and Furin: Implication in Lung Cancer Progression
Preprints.org·2024Open Access
GDF10 is a negative regulator of vascular calcification
Journal of Biological Chemistry·2024· 1 citedOpen Access
Corrigendum to “PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease” [Metabolism Volume 150, January 2024, 155736, PMID: 7967646]
Metabolism·2024Open Access
PCSK9 inhibition in myeloid cells enhances cardioprotection beyond its LDL cholesterol-lowering effects
2024· 1 citedOpen Access
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Frequent Co-authors

Michel Chrétien(20), Annik Prat(15), Suzanne Benjannet(14), Josée Hamelin(9), Claude Lazure(8), Jadwiga Marcinkiewicz(6), Robert Day(6), Richard A. Murphy(5), L. Alexandra Wickham(4), Majambu Mbikay(4), Sangeeta Pareek(4), Steve Poirier(4), Nasha Nassoury(4), Ajoy Basak(3), Rachid Essalmani(3), Marie‐Claude Asselin(3), Ann Chamberland(3), Jean Davignon(3), Seyed Javad Mowla(3), Ahmed Zaid(3)