Mirjam Luijten

National Institute for Public Health and the Environment — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index5.2kcitations171works1.32yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(69), Effects and risks of endocrine disrupting chemicals(33), Computational Drug Discovery Methods(20), Animal testing and alternatives(19), DNA Repair Mechanisms(16)

Publications171 total

P30-74 How advancements in OECD genotoxicity TGs improve chemical safety assessments and challenge retrospective data analysis for NAM based IATA development
Toxicology Letters·2025Open Access
Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies
Frontiers in Toxicology·2025Open Access
Advancing Genotoxicity Assessment by Building a Global <scp>AOP</scp> Network
Environmental and Molecular Mutagenesis·2025· 2 citedOpen Access
A Common Adverse Outcome Pathway for Metal(loid)s Inducing Nephrotoxicity to Advance Next-Generation Risk Assessment of Chemical Mixtures
The Annual Review of Pharmacology and Toxicology·2025· 1 citedOpen Access
Adverse Outcome Pathway (AOP) Coaching Program—how it functions and contributes to a more harmonized approach to AOP development and construction of AOP networks with regulatory utility
Environmental Toxicology and Chemistry·2025· 1 citedOpen Access
Towards a quantitative adverse outcome pathway for liver carcinogenesis: From proliferation to prediction
Computational Toxicology·2025Open Access
A pragmatic workflow for human relevance assessment of toxicological pathways and associated new approach methodologies
Regulatory Toxicology and Pharmacology·2025· 3 citedOpen Access
The European Partnership PARC’s role in actively promoting the uptake of new approach methodologies and next-generation risk assessment into regulatory risk assessment practice
Current Opinion in Toxicology·2025· 3 citedOpen Access
A global AOP network for genotoxicity to drive the integration of NAMs
2025Open Access
An Alternative Safety Profiling Algorithm (ASPA) to transform next generation risk assessment into a structured and transparent process
ALTEX·2025· 3 citedOpen Access
Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th <scp>International Workshop</scp> on <scp>Genotoxicity Testing</scp>
Environmental and Molecular Mutagenesis·2024· 4 citedOpen Access
S10-02 New Approach Methodologies (NAMs): a quantitative in vitro to in vivo extrapolation case study with perfluorinated compounds
Toxicology Letters·2024Open Access
S06-03 Next-generation testing strategies for quantitative assessment of genomic damage
Toxicology Letters·2024
Combined chronic dietary exposure to four nephrotoxic metals exceeds tolerable intake levels in the adult population of 10 European countries
Food Additives & Contaminants Part A·2023· 4 citedOpen Access
S23-01: Introduction to quantitative AOP models and their utility in toxicology and risk assessment
Toxicology Letters·2023
P22-09: Application of Weighted Gene Co-expression Network Analysis as Mode of Action Screening Method for Suspected Non-Genotoxic Carcinogens Inducing Oxidative Stress
Toxicology Letters·2023
S23-04: Making quantitative AOP Networks into Usable Tools for Risk Assessment
Toxicology Letters·2023
Oxidative DNA damage leading to chromosomal aberrations and mutations
OECD series on adverse outcome pathways·2023· 6 citedOpen Access
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project
Frontiers in Toxicology·2023· 23 citedOpen Access
New approach methodologies in human regulatory toxicology – Not if, but how and when!
Environment International·2023· 276 citedOpen Access
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Frequent Co-authors

Harry van Steeg(7), Jan van Benthem(7), Maria Uhl(5), Carole L. Yauk(5), Philip Marx‐Stoelting(4), Bob van de Water(4), Wieneke Bil(4), Joost P.M. Melis(4), Annemieke M. W. Spijkerman(4), Harold Snieder(4), Aldert H. Piersma(4), Andrew Williams(4), Raffaella Corvi(4), Abigail Jacobs(4), Paul Wackers(4), David Kirkland(4), Matthias Herzler(3), Marcel Leist(3), Claudia Gundacker(3), Jana V. van Vliet‐Ostaptchouk(3)