Adolfo Cavalié

Saarland University — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index4.2kcitations70works0.02yr avg
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Research Topics

Ion channel regulation and function(24), Endoplasmic Reticulum Stress and Disease(18), Ion Channels and Receptors(15), Cardiac electrophysiology and arrhythmias(11), Neuroscience and Neuropharmacology Research(9)

Publications70 total

Kinetics of the thapsigargin-induced Ca2+ mobilisation: A quantitative analysis in the HEK-293 cell line
Frontiers in Physiology·2023· 16 citedOpen Access
Editorial: The evolving picture of Ca2+ leak from endoplasmic reticulum in health and diseases
Frontiers in Physiology·2023· 5 citedOpen Access
Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer
Frontiers in Physiology·2022· 9 citedOpen Access
Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin
Life Science Alliance·2022· 15 citedOpen Access
Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state
Biochemical Journal·2021· 19 citedOpen Access
Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos
Cell Reports·2021· 12 citedOpen Access
Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells
Cell Calcium·2021· 10 citedOpen Access
Mycolactone enhances the Ca <sup>2+</sup> leakage from endoplasmic reticulum by trapping Sec61 translocons in a Ca <sup>2+</sup> permeable state
2021Open Access
Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state
Publications of the UdS (Saarland University)·2021Open Access
Eeyarestatin 24 impairs SecYEG‐dependent protein trafficking and inhibits growth of clinically relevant pathogens
Molecular Microbiology·2020· 10 citedOpen Access
Identification of signal peptide features for substrate specificity in human Sec62/Sec63‐dependent ER protein import
FEBS Journal·2020· 63 citedOpen Access
Proteomics identifies signal peptide features determining the substrate specificity in human Sec62/Sec63-dependent ER protein import
2019· 2 citedOpen Access
Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum
Cell chemical biology·2019· 53 citedOpen Access
In Situ, Light-Guided Axon Growth on Biomaterials via Photoactivatable Laminin Peptidomimetic IK(HANBP)VAV
ACS Applied Materials & Interfaces·2018· 19 cited
AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
Nature Communications·2018· 67 citedOpen Access
An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases
Frontiers in Physiology·2017· 154 citedOpen Access
Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)
Journal of Allergy and Clinical Immunology·2017· 80 citedOpen Access
The S4–S5 linker – gearbox of TRP channel gating
Cell Calcium·2017· 36 cited
Pathobiochemie des Sec61-Komplexes in der ER-Membran
BIOspektrum·2015· 1 cited
Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum
Journal of Biological Chemistry·2015· 36 citedOpen Access
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Frequent Co-authors

Veit Flockerzi(17), Richard Zimmermann(15), Stephan Philipp(12), Volkhard Helms(10), Ulrich Wissenbach(9), Sven Lang(9), Martin Jung(9), Marc Freichel(7), Claudia Trost(6), Nico Schäuble(6), Franz Hofmann(5), W. Trautwein(5), Stephanie Zimmer(5), Stefan Schorr(5), Johanna Dudek(5), D. Pelzer(4), Marie-Christine Klein(4), Markus Greiner(4), Igor Gamayun(4), Stefan Pfeffer(3)