Rick A. Wetsel

The University of Texas Health Science Center at Houston — United States

Immunology and Microbiology · Life Sciences

57h-index11.2kcitations180works0.02yr avg
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Research Topics

Complement system in diseases(96), Coagulation, Bradykinin, Polyphosphates, and Angioedema(23), Blood Coagulation and Thrombosis Mechanisms(21), Monoclonal and Polyclonal Antibodies Research(18), Blood groups and transfusion(15)

Publications180 total

Dysregulated Complement and Autophagy in Non-resolvable-COVID-19 Patients Requiring Lung Transplantation
2024
233 Activated C5ar1 signaling induces fibrogenic development in Mycobacterium avium (Mav)-infected mouse lungs via the proinflammatory T helper-type I cell response
Immunobiology·2023
239 Novel alternative polyadenylation as a post-transcriptional mechanism in C5ar1 signaling-dependent pleural hypertrophy and fibrosis in collagen-induced arthritic mice
Immunobiology·2023Open Access
C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation
Frontiers in Immunology·2023· 11 citedOpen Access
C5a Anaphylatoxin Receptor 1 Mediates Pleural Hypertrophy and Rheumatoid Lung Fibrosis in Collagen-induced Arthritic Mice
2023
Role of different pathways of the complement cascade in experimental bullous pemphigoid
UNC Libraries·2020Open Access
Circadian Clock and Complement Immune System—Complementary Control of Physiology and Pathology?
Frontiers in Cellular and Infection Microbiology·2020· 37 citedOpen Access
In response to complement anaphylatoxin peptides C3a and C5a, human vascular endothelial cells migrate and mediate the activation of B‐cells and polarization of T‐cells
The FASEB Journal·2020· 38 citedOpen Access
Complement Receptor 1 (CR1/CD35)-expressing retinal pigment epithelial cells as a potential therapy for age-related macular degeneration
Molecular Immunology·2019· 8 cited
Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility
Diabetes·2019· 91 citedOpen Access
A Preclinical Safety Study of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells for Macular Degeneration
Journal of Ocular Pharmacology and Therapeutics·2019· 8 citedOpen Access
The Second Receptor for C5a, C5aR2, Is Detrimental to Mice during Systemic Infection with <i>Listeria monocytogenes</i>
The Journal of Immunology·2019· 10 citedOpen Access
Generation of CDMLe012-A-1 cells: A pluripotent human embryonic stem cell model of Turner's syndrome
Stem Cell Research·2019· 1 citedOpen Access
Cigarette smoke–induced reduction of C1q promotes emphysema
JCI Insight·2019· 43 citedOpen Access
Correction: Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence
PLoS Pathogens·2019· 1 citedOpen Access
Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections
Virulence·2019· 31 citedOpen Access
Complement proteins associated with synapse proteins in an Alzheimer's disease mouse model lacking C5aR1
Molecular Immunology·2018
C5a modulates immune cell egression in lymphoid tissues via endothelial-dependent inducible nitric oxide synthase
Molecular Immunology·2018
Chronic intradermal C5a exposure stimulates cardiac fibrosis – A role of inflamed lymphatic endothelium
Molecular Immunology·2018
The second receptor for C5a, C5aR2, is detrimental to the host during systemic infection with Listeria monocytogenes
Molecular Immunology·2018
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Frequent Co-authors

John D. Lambris(8), Travis J. Hollmann(7), Scott R. Barnum(7), Scott M. Drouin(6), David L. Haviland(6), Brian F. Tack(5), V. Michael Holers(4), Jens Kildsgaard(4), Stacey L. Mueller‐Ortiz(4), Firas S. Zetoune(3), Peter A. Ward(3), Dachun Wang(3), Harvey R. Colten(3), David B. Corry(3), Trent M. Woodruff(3), J. Vidya Sarma(2), Thomas A. Neff(2), Guillermina Girardi(2), Jessica Berman(2), Patricia Redecha(2)