Stephen E. Fawell

Bioscience Research — United States

Computer Science · Physical Sciences

48h-index12.5kcitations445works1.02yr avg
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Research Topics

Computational Drug Discovery Methods(69), Melanoma and MAPK Pathways(51), Immune cells in cancer(39), PARP inhibition in cancer therapy(38), Cytokine Signaling Pathways and Interactions(35)

Publications444 total

Supplementary Figure 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Supplementary Figure 4 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Supplementary Figure 3 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Supplementary Table 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Supplementary Figure 5 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Supplementary Figure 2 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025Open Access
Development and characterization of a potent and selective BLIMP1 protac as a novel, first-in-class therapy for multiple myeloma
Blood·2025Open Access
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
Journal of Medicinal Chemistry·2025· 2 cited
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor
Journal of Medicinal Chemistry·2025· 15 cited
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
Journal of Medicinal Chemistry·2024· 22 cited
146 (PB134): First disclosure of AZD3470, a highly potent MTA-cooperative PRMT5 inhibitor in PRIMROSE and PRIMAVERA clinical studies
European Journal of Cancer·2024· 1 cited
150 (PB138): AZD3470 induces regressions and durable responses in MTAPdeficient tumor models of diverse tumor indications
European Journal of Cancer·2024
Supplementary Figure 3 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Figure 4 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Figure 5 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Figure 5 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Figure 4 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Figure 1 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Data from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
Supplementary Table 1 from Novel arginase inhibitor, AZD0011, demonstrates immune cell stimulation and anti-tumor efficacy with diverse combination partners
2024Open Access
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Frequent Co-authors

Michael Zinda(10), Alwin G. Schuller(8), Corinne Reimer(8), Huawei Chen(7), Leigh Zawel(6), Malcolm G. Parker(6), Jeffrey W. Johannes(5), Maureen M. Hattersley(5), Paul D. Lyne(5), James Barsoum(4), Ammar Adam(4), Elisabetta Chiarparin(4), Justin Cidado(4), Eric T. Gangl(4), Nancy Su(4), Edwin Clark(4), David M. Wilson(4), Mark J. O’Connor(4), Gordon B. Mills(4), Elisabetta Leo(4)