Helena J. Janse van Rensburg

North-West University — South Africa

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index1.1kcitations34works1.52yr avg
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Research Topics

Hippo pathway signaling and YAP/TAZ(19), Synthesis and biological activity(5), Research on Leishmaniasis Studies(4), Wnt/β-catenin signaling in development and cancer(4), Cellular Mechanics and Interactions(3)

Publications34 total

Synthesis and in vitro antitrypanosomatid efficacy of 5-benzylidene-2-thiohydantoin esters
Medicinal Chemistry Research·2025Open Access
In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone
Drug Development Research·2025· 3 citedOpen Access
Flavone and Flavonol derivatives as adenosine A1/A2A receptor ligands: Structure-affinity insights
Results in Chemistry·2025· 1 citedOpen Access
Synthesis and in vitro antitrypanosomatid activity of novel 5-nitroindole-rhodanine conjugates
Future Medicinal Chemistry·2025· 2 citedOpen Access
Flavone and Flavonol Derivatives as Adenosine A1/A2a Receptor Ligands: Structure-Affinity Insights
SSRN Electronic Journal·2025Open Access
Exploration of Novel “Ferroxazide/Ferrazone” Derivatives as Antitrypanosomatid Agents: Design, Synthesis, and Biological Efficacy
Applied Organometallic Chemistry·2024· 3 citedOpen Access
Evaluation of chemical constituents of Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) as adenosine A1/A2A receptor ligands
Medicinal Chemistry Research·2023· 5 citedOpen Access
Remitting Seronegative Symmetrical Synovitis with Pitting Edema: A Case Report of an Immune-Related Adverse Event following Surgery
Case Reports in Oncology·2023· 2 citedOpen Access
A tailored phase I-specific patient-reported outcome (PRO) survey to capture the patient experience of symptomatic adverse events
British Journal of Cancer·2023· 15 citedOpen Access
Supplementary Data - Publication Only from The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
2023Open Access
Data from The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
2023Open Access
Data from The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
2023Open Access
Supplementary Data - Publication Only from The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
2023Open Access
Longitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy
Cell Death and Disease·2023· 30 citedOpen Access
Longitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy
Research Square (Research Square)·2022Open Access
Circulating Biomarkers for Therapeutic Monitoring of Anti-cancer Agents
The Oncologist·2022· 17 citedOpen Access
Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic
ACS Nanoscience Au·2021· 21 citedOpen Access
The Hippo Pathway, Immunity, and Cancer: An update
2020Open Access
Rox8 promotes microRNA-dependent <i>yki</i> messenger RNA decay
Proceedings of the National Academy of Sciences·2020· 18 citedOpen Access
Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors
Cancers·2019· 58 citedOpen Access
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Frequent Co-authors

Taha Azad(14), Xiaolong Yang(14), Yawei Hao(7), Prem Khanal(7), Brooke Snetsinger(6), Lori M. Minassian(6), Charles H. Graham(6), Michael J. Rauh(6), Yawei Hao(5), Xiaolong Yang(5), Kazem Nouri(4), Pavlina Spiliopoulou(4), Lillian L. Siu(4), Janine Aucamp(4), Keisuke Suganuma(4), David D. N’Da(4), Min Ling(4), Ling Min(3), Philippe L. Bédard(3), Aaron R. Hansen(3)