Xin Tian

Yale University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index4.4kcitations50works3.42yr avg
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Research Topics

Genetic and Kidney Cyst Diseases(36), Renal and related cancers(21), Biomedical Research and Pathophysiology(14), Microtubule and mitosis dynamics(6), Genetic Syndromes and Imprinting(6)

Publications50 total

Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease
Journal of the American Society of Nephrology·2025Open Access
Glis3 is a modifier of cyst progression in autosomal dominant polycystic kidney disease
2025
Anks3 mediates cilia dependent polycystin signaling and is essential for adult kidney homeostasis
2025· 4 citedOpen Access
Functional Studies of Polycystin-1 Using a Novel Pkd1-HaloTag Mouse
Journal of the American Society of Nephrology·2024
Chemical Modulation of the Ire1α-Xbp1 Pathway Reduces Cyst Size in ADPKD Mouse and Human Three-Dimensional Spheroids
Journal of the American Society of Nephrology·2024
Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Journal of the American Society of Nephrology·2024
Glis2 is an early effector of polycystin signaling and a target for therapy in polycystic kidney disease
Nature Communications·2024· 20 citedOpen Access
Dephosphorylation Facilitates Trafficking of Mutant Polycystin-2 to Cilia
Journal of the American Society of Nephrology·2023
Effects of ultra-high pressure assisted extraction on the structure, antioxidant and hypolipidemic activities of Porphyra haitanensis polysaccharides
Food Chemistry·2023· 43 cited
Dnajb11-Kidney Disease Develops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice
Journal of the American Society of Nephrology·2023· 8 citedOpen Access
Abstract 689: Loss of Smooth Muscle Cell Nogo-B Protects from Atherosclerosis Plaque Development
Arteriosclerosis Thrombosis and Vascular Biology·2023
Pkd2 Re-Expression Can Reverse Liver Cysts and Improve GFR in Mouse Models of Autosomal Dominant Polycystic Kidney Disease
Journal of the American Society of Nephrology·2022
Renal plasticity revealed through reversal of polycystic kidney disease in mice
Nature Genetics·2021· 113 citedOpen Access
Restoration of proximal tubule flow–activated transport prevents cyst growth in polycystic kidney disease
JCI Insight·2021· 9 citedOpen Access
Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease
Journal of the American Society of Nephrology·2020· 53 citedOpen Access
Overexpression of Iris lactea tonoplast Na<sup>+</sup>/H<sup>+</sup> antiporter gene IlNHX confers improved salt tolerance in tobacco
Biologia Plantarum·2020· 24 citedOpen Access
Cell-Autonomous Hedgehog Signaling Is Not Required for Cyst Formation in Autosomal Dominant Polycystic Kidney Disease
Journal of the American Society of Nephrology·2019· 28 citedOpen Access
Oral administration of hydroxylated-graphene quantum dots induces intestinal injury accompanying the loss of intestinal stem cells and proliferative progenitor cells
Figshare·2019Open Access
[Effect of early supplementation of exogenous carnitine on liver mitochondrial damage in severely scalded rats and its pathological mechanism].
PubMed·2018· 1 cited
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts
Journal of the American Society of Nephrology·2016· 58 citedOpen Access
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Frequent Co-authors

Stefan Somlo(37), Yiqiang Cai(11), Ke Dong(10), Peter Igarashi(8), Zemeng Wei(8), Ming Ma(6), Michael Rehman(6), Adrián Cordido(6), Zhiheng Yu(4), Michihiro Mitobe(4), Sorin V. Fedeles(4), Anna‐Rachel Gallagher(4), Jianlei Gu(4), Hongyu Zhao(4), Saori Nishio(3), Véronique Chauvet(3), Hervé Husson(3), Thomas Hieseberger(3), Anton M. Bennett(3), Oxana Ibraghimov‐Beskrovnaya(3)