Yu Chen

Nanjing Agricultural University — China

Medicine · Health Sciences

65h-index29.3kcitations551works2.92yr avg
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Research Topics

Prostate Cancer Treatment and Research(197), Epigenetics and DNA Methylation(48), Cancer Genomics and Diagnostics(38), Gastrointestinal Tumor Research and Treatment(36), Cancer-related gene regulation(35)

Publications551 total

Abstract B013: Chromosomal rearrangements at the YAP/TAZ pathway genes are associated with heterogeneity and stem cell-like castration-resistant prostate cancer
Cancer Research·2025
NSD2 targeting reverses plasticity and drug resistance in prostate cancer
Nature·2025· 2 citedOpen Access
PRC2 Restricts Malignant Peripheral Nerve Sheath Tumorigenesis in a Genetically Engineered Mouse Model of MPNST
2025
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
UNC Libraries·2025Open Access
ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L
Nature Genetics·2025· 5 citedOpen Access
Review of Chinese medicine intervention in PI3K/AKT pathway to regulate fibrosis
Medicine·2025· 2 citedOpen Access
Genomic alterations in the YAP/TAZ pathway are associated with stem cell-like castration-resistant prostate cancer
2025Open Access
Reprogramming of human urine cells into cardiomyocytes via a small molecule cocktail in xeno-free conditions
Communications Medicine·2025· 1 citedOpen Access
Disruption of TAD hierarchy promotes LTR co-option in cancer
Nature Genetics·2025· 3 citedOpen Access
BET inhibitors reduce tumor growth in preclinical models of gastrointestinal gene signature–positive castration-resistant prostate cancer
Journal of Clinical Investigation·2025· 2 citedOpen Access
Pan-cancer analysis identifies DBF4B as an immunologic and prognostic biomarker
Journal of Cancer·2025Open Access
Single microorganism RNA sequencing of microbiomes using smRandom-Seq
Nature Protocols·2025· 3 cited
Corrigendum: Development and validation of a simulation training platform for the ligation of deep dorsal vein complex in radical prostatectomy
Frontiers in Oncology·2025Open Access
Author response for "Microneedle-Based Nanomotor Cancer Vaccine Combined with Chemotherapy for Synergistic Melanoma Therapy"
2025
Abstract 3883: Evolution of genomic and epigenomic heterogeneity in prostate cancer from tissue and liquid biopsies
Cancer Research·2025· 1 cited
A multi‐omics analysis reveals candidate genes for Cd tolerance in Paspalum vaginatum
BMC Plant Biology·2025Open Access
Loss of <i>Kmt2c</i> / <i>d</i> promotes gastric cancer initiation and confers vulnerability to mTORC1 inhibition and anti-PD1 immunotherapy
2025· 1 citedOpen Access
Author Correction: LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer
Cell Research·2025Open Access
Identification of GDP as a small inhibitory molecule in HepG2 cells by non‑targeted metabolomics analysis
Oncology Letters·2025· 2 citedOpen Access
Spatial proximity of CD8+ T cells to tumor cells predicts neoadjuvant therapy efficacy in breast cancer
npj Breast Cancer·2025· 15 citedOpen Access
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Frequent Co-authors

Dong Gao(15), Charles L. Sawyers(13), Andrea Sboner(11), Howard I. Scher(10), John Wongvipat(10), Ping Chi(10), Mark A. Rubin(9), Himisha Beltran(8), Anuradha Gopalan(7), Leili Ran(6), Deyou Zheng(6), Francesca Demichelis(5), Vivek Arora(5), Wouter R. Karthaus(5), Zhen Cao(5), Juan Miguel Mosquera(4), Brian D. Robinson(4), Olivier Elemento(4), Christopher E. Barbieri(4), Brett S. Carver(4)