Chao Wang

MRC Laboratory of Molecular Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index545citations33works1.52yr avg
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Research Topics

Biochemical and Molecular Research(9), HIV/AIDS drug development and treatment(6), RNA Interference and Gene Delivery(5), Pneumocystis jirovecii pneumonia detection and treatment(4), Mosquito-borne diseases and control(3)

Publications32 total

Termination of the integrated stress response
Science·2025Open Access
Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem·2025Open Access
Small‐Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells
ChemMedChem·2024· 1 citedOpen Access
Mass immunisation to eradicate Japanese encephalitis: Real-world evidence from Guizhou Province in 2005–2021
Journal of Virus Eradication·2024· 5 citedOpen Access
Inhibitors of Aspartate Transcarbamoylase Inhibit <i>Mycobacterium tuberculosis</i> Growth
ChemMedChem·2023· 7 citedOpen Access
Allosteric inhibitors of aspartate transcarbamoylase: targeting pyrimidine biosynthesis to address multiple diseases
2023Open Access
Discovery of Small-Molecule Allosteric Inhibitors of <i>Pf</i>ATC as Antimalarials
Journal of the American Chemical Society·2022· 18 citedOpen Access
The state of the art of PROTAC technologies for drug discovery
European Journal of Medicinal Chemistry·2022· 103 cited
Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase
Frontiers in Cellular and Infection Microbiology·2022· 12 citedOpen Access
Total Synthesis of Three Isomers of Entecavir
SSRN Electronic Journal·2022Open Access
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein
Journal of Medicinal Chemistry·2021· 37 citedOpen Access
Characterization of cysteine sulfinic acid decarboxylase from Tribolium castaneum and its application in the production of β-alanine
Applied Microbiology and Biotechnology·2019· 23 cited
Oligomeric protein interference validates druggability of aspartate interconversion in <i>Plasmodium falciparum</i>
MicrobiologyOpen·2019· 7 citedOpen Access
Clinical and genetic analysis of 7 Chinese patients with β-ureidopropionase deficiency
Medicine·2019· 10 citedOpen Access
Annealing novel nucleobase-lipids with oligonucleotides or plasmid DNA based on H-bonding or π-π interaction: Assemblies and transfections
Biomaterials·2018· 45 citedOpen Access
Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase
Biochemical and Biophysical Research Communications·2018· 22 citedOpen Access
Characterization of the inserted mutagenesis dextransucrases from Leuconostoc mesenteroides 0326 to produce hyperbranched dextran
International Journal of Biological Macromolecules·2018· 10 cited
Design, synthesis, crystal structure and<i>in vitro</i>cytotoxic properties of a novel Schiff base derived from indole and biphenyl
Acta Crystallographica Section C Structural Chemistry·2017· 10 cited
Alkylation of phosphorothioated thrombin binding aptamers improves the selectivity of inhibition of tumor cell proliferation upon anticoagulation
Biochimica et Biophysica Acta (BBA) - General Subjects·2017· 15 citedOpen Access
Sensitive and selective electrochemical detection of artemisinin based on its reaction with p-aminophenylboronic acid
Analytica Chimica Acta·2016· 21 cited
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Frequent Co-authors

Shiqi Peng(9), Matthew R. Groves(8), Alexander Dömlingꝉ(7), Carsten Wrenger(5), Xiaochen Du(5), Ming Zhao(4), Bidong Zhang(3), Yuejie Zhu(2), Xiantao Yang(2), Zhu Guan(2), Lihe Zhang(2), Zhenjun Yang(2), Angel J. Ruiz‐Moreno(2), Sergey Lunev(2), Soraya S. Bosch(2), Fernando de Assis Batista(2), Marleen Linzke(2), Ming Zhao(2), Arne Krüger(2), Lidia Visser(2)