Hiroo Yamaguchi

Kyushu University — Japan

Medicine · Health Sciences

21h-index3.2kcitations79works4.72yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(15), Orthodontics and Dentofacial Orthopedics(10), Neuroinflammation and Neurodegeneration Mechanisms(10), Temporomandibular Joint Disorders(9), Cleft Lip and Palate Research(9)

Publications78 total

Facilitated αlpha-synuclein oligomer transfer via a connexin inhibitor mitigates neuronal αlpha-synuclein burden and disease progression in an MSA-C model
Journal of the Neurological Sciences·2025
A unique microglia subset associated with aggressive α-synucleinopathy uncovered in a rapidly progressive multiple system atrophy cerebellar type model
Neurobiology of Disease·2025· 1 citedOpen Access
Facilitated α-synuclein oligomer sharing among glial cells by a centrally acting connexin inhibitor attenuates a rapidly progressive multiple system atrophy-cerebellar type model by reducing the neuronal α-synuclein burden
Acta Neuropathologica Communications·2025· 1 citedOpen Access
Blood exosome connexins and small <scp>RNAs</scp> related to demyelinating disease activity
Annals of Clinical and Translational Neurology·2025· 2 citedOpen Access
A rapidly progressive multiple system atrophy-cerebellar variant model presenting marked glial reactions with inflammation and spreading of α-synuclein oligomers and phosphorylated α-synuclein aggregates
Brain Behavior and Immunity·2024· 13 cited
Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model
Scientific Reports·2024· 11 citedOpen Access
Iguratimod Ameliorates the Severity of Secondary Progressive Multiple Sclerosis in Model Mice by Directly Inhibiting IL-6 Production and Th17 Cell Migration via Mitigation of Glial Inflammation
Biology·2023· 3 citedOpen Access
Iguratimod Ameliorates the Severity of Secondary Progressive Multiple Sclerosis in Model Mice by Directly Inhibiting IL-6 Production and Th17 Cell Migration via Mitigation of Glial Inflammation
Preprints.org·2023· 5 citedOpen Access
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy
Brain Pathology·2022· 9 citedOpen Access
Applicability of Weighting Method as Measure for Existing Manholes against Uplifting during Liquefaction
Applied Sciences·2022· 9 citedOpen Access
Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
Journal of Neuroinflammation·2021· 18 citedOpen Access
Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior
Brain Behavior and Immunity·2021· 43 citedOpen Access
Early decrease in intermediate monocytes in peripheral blood is characteristic of multiple system atrophy-cerebellar type
Journal of Neuroimmunology·2020· 6 cited
Comparison of Maximum Mouth Opening Following Mandibular Bilateral Sagittal Splitting Ramus osteotomies in Class III Females Using Two Different Osteosynthesis Methods
Journal of Oral Rehabilitation·2020· 2 cited
Author response for "Comparison of Maximum Mouth Opening Following Mandibular Bilateral Sagittal Splitting Ramus osteotomies in Class III Females Using Two Different Osteosynthesis Methods"
2020Open Access
Author response for "Comparison of Maximum Mouth Opening Following Mandibular Bilateral Sagittal Splitting Ramus osteotomies in Class III Females Using Two Different Osteosynthesis Methods"
2020
Expression of Mutant Human α-synuclein in Oligodendrocytes during Myelination Period Induces Remarkable Glial Inflammation and Demyelination in the Spinal Cord and Brainstem/Cerebellar White Matter: a Novel Model of Multiple System Atrophy-Cerebellar Type and Primary Progressive Multiple Sclerosis (4126)
Neurology·2020
Temporal expression profiling of DAMPs-related genes revealed the biphasic post-ischemic inflammation in the experimental stroke model
Molecular Brain·2020· 35 citedOpen Access
Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis
Proceedings of the National Academy of Sciences·2020· 49 citedOpen Access
A long-term follow-up case of skeletal Class II malocclusion treated by orthognathic surgery
2020
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Frequent Co-authors

Jun‐ichi Kira(22), Ryo Yamasaki(20), Katsuhisa Masaki(14), Noriko Isobe(11), Nobuo Inoue(10), Jie Shen(8), Takuya Matsushita(8), Kazuhiro Matsushita(8), Satoshi Nagata(6), Mitsuru Watanabe(6), Kazuhiro Ooi(6), Yusaku Nakabeppu(5), Akio Hiwatashi(5), Yasunori Totsuka(5), Ezgi Ozdemir Takase(5), Yiwen Cui(4), Dai Matsuse(4), Tadashi Mikoya(4), Kanchu Tei(4), Youren Tong(3)