Yi Lee

Karolinska Institutet — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index15.3kcitations24works0.02yr avg
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Research Topics

Extracellular vesicles in disease(20), MicroRNA in disease regulation(13), RNA Interference and Gene Delivery(8), Cell Adhesion Molecules Research(6), Complement system in diseases(2)

Publications22 total

Identification of storage conditions stabilizing extracellular vesicles preparations
Journal of Extracellular Vesicles·2022· 363 citedOpen Access
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles
Nature Biomedical Engineering·2021· 98 citedOpen Access
Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion
Cells·2021· 19 citedOpen Access
Profiling of extracellular small RNAs highlights a strong bias towards non-vesicular secretion
2020· 1 citedOpen Access
Turnaround Time of Plasma Next-Generation Sequencing in Thoracic Oncology Patients: A Quality Improvement Analysis
JCO Precision Oncology·2020· 28 citedOpen Access
Engineering of extracellular vesicles for display of protein biotherapeutics
2020· 8 citedOpen Access
Considerations and Implications in the Purification of Extracellular Vesicles – A Cautionary Tale
Frontiers in Neuroscience·2019· 49 citedOpen Access
Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging
Journal of Extracellular Vesicles·2019· 176 citedOpen Access
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
Scientific Reports·2018· 137 citedOpen Access
Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
Scientific Reports·2017· 245 citedOpen Access
Methodological Guidelines to Study Extracellular Vesicles
Circulation Research·2017· 1.0k citedOpen Access
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
Brain·2017· 151 citedOpen Access
Preparation and isolation of siRNA-loaded extracellular vesicles
Utrecht University Repository (Utrecht University)·2017
Preparation and Isolation of siRNA-Loaded Extracellular Vesicles
Methods in molecular biology·2016· 9 cited
Cells release subpopulations of exosomes with distinct molecular and biological properties
Scientific Reports·2016· 924 citedOpen Access
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
Nanomedicine Nanotechnology Biology and Medicine·2015· 647 citedOpen Access
Purification and characterization of extracellular vesicles released from pluripotent stem cells
2015
Serum‐free culture alters the quantity and protein composition of neuroblastoma‐derived extracellular vesicles
Journal of Extracellular Vesicles·2015· 181 citedOpen Access
Extracellular vesicles for delivery of small RNA
2014
Exosome-mediated delivery of siRNA in vitro and in vivo
Nature Protocols·2012· 598 cited
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Frequent Co-authors

Samir EL Andaloussi(18), Matthew J. A. Wood(15), Imre Mäger(14), Joel Z. Nordin(11), Pieter Vader(10), Giulia Corso(8), Oscar P. B. Wiklander(7), Helena Sork(6), Henrik J. Johansson(5), André Görgens(5), Smith Rjh(4), Janne Lehtiö(4), Yiqi Seow(4), Mariana Conceição(4), Roosmarijn E. Vandenbroucke(4), Manuela O. Gustafsson(3), Rakibe Beklem Bostancıoğlu(3), Xiuming Liang(3), Dara K. Mohammad(3), Justin Hean(3)