Taksim Ahmed

Broad Institute — United States

Materials Science · Physical Sciences

14h-index826citations31works15.02yr avg
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Research Topics

Nanoparticle-Based Drug Delivery(10), RNA Interference and Gene Delivery(7), Lipid Membrane Structure and Behavior(6), Phytochemicals and Antioxidant Activities(4), Alzheimer's disease research and treatments(4)

Publications31 total

Designing lipid nanoparticles using a transformer-based neural network
Nature Nanotechnology·2025· 16 citedOpen Access
An update on strategies for optimizing polymer-lipid hybrid nanoparticle-mediated drug delivery: exploiting transformability and bioactivity of PLN and harnessing intracellular lipid transport mechanism
Expert Opinion on Drug Delivery·2024· 14 cited
Physical methods to overcome tissue barriers in vaccine delivery
Vaccine Insights·2023Open Access
Brain‐Penetrating and Disease Site‐Targeting Manganese Dioxide‐Polymer‐Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways
Advanced Science·2023· 31 citedOpen Access
Remodeling Tumor Immune Microenvironment by Using Polymer-Lipid-Manganese Dioxide Nanoparticles with Radiation Therapy to Boost Immune Response of Castration-Resistant Prostate Cancer
Research·2023· 62 citedOpen Access
Improving Vascular Functions by Bioreactive Nanoparticles for Treatment of Alzheimer’s Disease
Alzheimer s & Dementia·2022
Development of Smart Nanoparticle Systems for the Treatment of Cancer and Central Nervous System (CNS) Diseases
TSpace·2022
Advances in Nanomedicine Design: Multidisciplinary Strategies for Unmet Medical Needs
Molecular Pharmaceutics·2022· 13 cited
Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma
Pharmaceutical Research·2021· 24 cited
Exploring the transformability of polymer-lipid hybrid nanoparticles and nanomaterial-biology interplay to facilitate tumor penetration, cellular uptake and intracellular targeting of anticancer drugs
Expert Opinion on Drug Delivery·2021· 21 cited
Microneedle Systems for Vaccine Delivery: the story so far
Expert Review of Vaccines·2020· 48 cited
Multifunctional bioreactive-nanoconstructs for sensitive and accurate MRI of cerebrospinal fluid pathology and intervention of Alzheimer’s disease
Nano Today·2020· 23 cited
Protective effect of chloroform extract of <i>Stereospermum chelonoides</i> bark against amyloid beta42 induced cell death in SH-SY5Y cells and against inflammation in Swiss albino mice
Journal of Basic and Clinical Physiology and Pharmacology·2018· 1 cited
Importance of integrating nanotechnology with pharmacology and physiology for innovative drug delivery and therapy – an illustration with firsthand examples
Acta Pharmacologica Sinica·2018· 105 citedOpen Access
Two‐Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2‐Positive Breast Cancer
Advanced Functional Materials·2018· 45 cited
Diruthenium(<scp>ii</scp>,<scp>iii</scp>) metallodrugs of ibuprofen and naproxen encapsulated in intravenously injectable polymer–lipid nanoparticles exhibit enhanced activity against breast and prostate cancer cells
Nanoscale·2017· 67 citedOpen Access
Design of nanocarriers for nanoscale drug delivery to enhance cancer treatment using hybrid polymer and lipid building blocks
Nanoscale·2016· 164 cited
Interactions Between DNA and Gemini Surfactant: Impact on Gene Therapy: Part I
Nanomedicine·2016· 86 cited
Interactions Between DNA and Gemini Surfactant: Impact on Gene Therapy: Part II
Nanomedicine·2016· 30 cited
Langmuir-Blodgett Monolayer Studies of Mixed Gemini Surfactant-Phospholipid Monolayers system for Gene Therapy Applications.
UWSpace (University of Waterloo)·2015· 2 citedOpen Access
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Frequent Co-authors

Xiao Yu Wu(12), Andrew M. Rauth(9), Chunsheng He(7), Jeffrey T. Henderson(7), Azhar Z. Abbasi(5), Lily Yi Li(4), Warren D. Foltz(4), Fuh-Ching Franky Liu(4), Ruixue Zhang(3), HoYin Lip(3), Azhar Z. Abbasi(3), Elliya Park(3), Paul E. Fraser(3), Mohammad Nasir Uddin(3), M. Rabiul Islam(3), Jason Li(2), Mohammad Amini(2), Brian Lu(2), Amany O. Kamel(2), Shawn Wettig(2)