Luis J. Cruz

Leiden University Medical Center — Netherlands

Immunology and Microbiology · Life Sciences

51h-index8.0kcitations191works2.82yr avg
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Research Topics

Immunotherapy and Immune Responses(55), Nanoplatforms for cancer theranostics(48), Photodynamic Therapy Research Studies(21), Nanoparticle-Based Drug Delivery(20), Osteoarthritis Treatment and Mechanisms(19)

Publications191 total

Therapeutic efficacy of extracellular vesicles from hiPSC-derived MSCs in serum-containing and xeno-free media for osteoarthritis treatment
Stem Cell Research & Therapy·2026Open Access
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Advanced Science·2025Open Access
Therapeutic efficacy of hiMSC-derived Extracellular Vesicles from Serum-containing and Xeno-free media for osteoarthritis treatment
2025· 1 citedOpen Access
Evaluating the Therapeutic Efficacy of Iopanoic Acid in a DMM-Induced Osteoarthritis Mouse Model and Osteochondral Lesioned Human Explants
2025· 1 citedOpen Access
M1 Macrophage Extracellular Vesicles and TLR3 Agonist Nanoparticles Down‐Regulate Immunosuppression and Metastasis via AKT/TAM in Triple‐Negative Breast Cancer
Molecular Carcinogenesis·2025· 2 citedOpen Access
Advancing Therapeutic Solutions: Poloxamer-based Thermosensitive Injectable Hydrogels containing a Self-assembling Peptide for <i>In situ</i> Gelation in an Osteoarthritis Murine Model
2025· 1 citedOpen Access
Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer
Vaccines·2025· 4 citedOpen Access
Poloxamer-based thermosensitive injectable hydrogels containing a self-assembling peptide for In situ gelation
Computational and Structural Biotechnology Journal·2025· 1 citedOpen Access
Impact of N-Terminal PEGylation on Synthesis and Purification of Peptide-Based Cancer Epitopes for Pancreatic Ductal Adenocarcinoma (PDAC)
ACS Omega·2024· 1 citedOpen Access
Therapeutic liposomal combination to enhance chemotherapy response and immune activation of tumor microenvironment
Journal of Controlled Release·2024· 10 citedOpen Access
Pharmacological Evaluation of Sambong Blumea balsamifera on Diuretic and Kidney Stone Dissolution Effects
Journal of Advances in Medicine and Pharmaceutical Sciences·2024· 1 citedOpen Access
Application of Doxorubicin-loaded PLGA nanoparticles targeting both tumor cells and cancer-associated fibroblasts on 3D human skin equivalents mimicking melanoma and cutaneous squamous cell carcinoma
Biomaterials Advances·2024· 15 citedOpen Access
Correction: Yu et al. Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles. Pharmaceutics 2022, 14, 840
Pharmaceutics·2024Open Access
Correction: Yu et al. Rare-Earth-Metal (Nd3+, Ce3+ and Gd3+)-Doped CaF2: Nanoparticles for Multimodal Imaging in Biomedical Applications. Pharmaceutics 2022, 14, 2796
Pharmaceutics·2023· 1 citedOpen Access
AGED MICROGLIA PROMOTE PRO-INFLAMMATORY MICROENVIRONMENT AND TUMOUR GROWTH ARREST
IBRO Neuroscience Reports·2023Open Access
Dual‐Targeting Nanoliposome Improves Proinflammatory Immunomodulation of the Tumor Microenvironment
Advanced Healthcare Materials·2023· 7 citedOpen Access
An EGF-modified PLGA-lanthanide nanoplatform for combined NIR-II cancer imaging and targeted drug delivery
2023Open Access
Erythrocyte−cancer hybrid membrane-coated reduction-sensitive nanoparticles for enhancing chemotherapy efficacy in breast cancer
Biomaterials Advances·2023· 28 citedOpen Access
Enhancing anti-tumor immunity through liposomal oxaliplatin and localized immunotherapy via STING activation
Journal of Controlled Release·2023· 68 citedOpen Access
Data from Targeting of &lt;sup&gt;111&lt;/sup&gt;In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells
2023Open Access
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Frequent Co-authors

Carl G. Figdor(15), Ferry Ossendorp(12), Paul J. Tacken(10), Alan Chan(10), I. Jolanda M. de Vries(9), Fernando Alberício(8), Clemens W.G.M. Löwik(6), Jurjen Tel(5), Félix Rueda(5), Candido G. Da Silva(5), Ivo Que(5), Mangala Srinivas(4), Remco Fokkink(4), Gerty Schreibelt(4), Marcelo J. Kogan(4), Christina Eich(4), Raimundo Fernandes de Araújo Júnior(4), Ruurd Torensma(3), Rodney Alexander Rosalia(3), Marcel Camps(3)