David Liu

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

62h-index23.0kcitations579works4.82yr avg
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Research Topics

Cancer Genomics and Diagnostics(126), Cancer Immunotherapy and Biomarkers(72), Bioinformatics and Genomic Networks(47), Genetics, Bioinformatics, and Biomedical Research(42), Immunotherapy and Immune Responses(38)

Publications578 total

Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy
2025Open Access
Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells
2025· 2 citedOpen Access
Real‐World Outcomes of Adjuvant Therapy in Stage III Melanoma and the Impact of Somatic Mutations
Cancer Medicine·2025· 1 citedOpen Access
Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy
2025Open Access
Bone marrow spatial architecture predicts response duration in smoldering multiple myeloma patients receiving checkpoint inhibitor therapy
Blood·2025
Understanding tumor-immune-stromal dynamics driving response and resistance to immune checkpoint blockade in melanoma 4125
The Journal of Immunology·2025Open Access
380 Cutaneous eruptions associated with lifileucel, a first-in-class tumor-infiltrating lymphocyte therapy, and interleukin-2 in individuals with metastatic melanoma: a retrospective prognostic analysis
Regular and Young Investigator Award Abstracts·2025Open Access
Corrigendum to Policies, resource allocation, and interventions for child and adolescent mental health in low- and middle-income countries in the Western Pacific Region: a scoping review [The Lancet Regional Health—Western Pacific, Vol 62 (2025), 101674]
The Lancet Regional Health - Western Pacific·2025Open Access
488 Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma
Regular and Young Investigator Award Abstracts·2025Open Access
Comparative analysis of CRISPR-Cas9, lentiviral transduction, and base editing for sickle cell disease in a murine model
Blood Advances·2025Open Access
Multiomic profiling of a unique in-transit melanoma cohort identifies melanoma differentiation as predictor of tumor progression and therapy response
2025Open Access
Ultrasmall Chemogenetic Tags with Group‐Transfer Ligands
Angewandte Chemie·2025
Ultrasmall Chemogenetic Tags with Group‐Transfer Ligands
Angewandte Chemie International Edition·2025· 1 cited
PREPRINT: AI-based approach for constraining the thermal evolution of Earth’s upper crust through automated digital fission-track analysis
2025Open Access
YAP1 drives aggressive and therapy resistant state in melanoma through reprogramming the chromatin and regulating immune evasive programs
2025Open Access
Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma
Nature Communications·2025· 6 citedOpen Access
Policies, resource allocation, and interventions for child and adolescent mental health in low- and middle-income countries in the Western Pacific Region: a scoping review
The Lancet Regional Health - Western Pacific·2025· 4 citedOpen Access
Defensive tolerance drives the reprogramming and dysfunction of infiltrating pathogenic B cells assuring the maintenance of tolerance
2025Open Access
Specific oncogene activation of the cell of origin in mucosal melanoma
Nature Communications·2025· 1 citedOpen Access
Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants
Cell Reports Medicine·2025· 7 citedOpen Access
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Frequent Co-authors

Eliezer M. Van Allen(17), Levi A. Garraway(6), Brendan Reardon(5), Nikolaus Schultz(5), Claire A. Margolis(5), Diana Miao(5), Deborah Schrag(4), Genevieve M. Boland(4), Keith T. Flaherty(4), Natalie I. Vokes(4), Haitham Elmarakeby(4), Stephanie A. Wankowicz(4), Lynette M. Sholl(4), Joaquim Bellmunt(4), Kent W. Mouw(4), Debyani Chakravarty(3), Jianjiong Gao(3), Ritika Kundra(3), Charles L. Sawyers(3), David B. Solit(3)