Toshio Hirano

Hokkaido University — Japan

Medicine · Health Sciences

93h-index37.5kcitations286works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(82), T-cell and B-cell Immunology(43), Immune Cell Function and Interaction(38), Protein Tyrosine Phosphatases(24), Immunotherapy and Immune Responses(23)

Publications284 total

IL-6 in inflammation, autoimmunity and cancer
International Immunology·2020· 1.3k citedOpen Access
How COVID-19 induces cytokine storm with high mortality
Inflammation and Regeneration·2020· 685 citedOpen Access
Renin–angiotensin system inhibitors and the severity of coronavirus disease 2019 in Kanagawa, Japan: a retrospective cohort study
Hypertension Research·2020· 50 citedOpen Access
COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
Immunity·2020· 803 citedOpen Access
Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis
Scientific Reports·2019· 50 citedOpen Access
Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines
Immunity·2019· 509 citedOpen Access
Naïve T Cell Homeostasis Regulated by Stress Responses and TCR Signaling
Frontiers in Immunology·2015· 8 citedOpen Access
The transition of radio-nuclides concentration deposited on Shizuoka Prefecture after the accident at Fukushima Dai-ichi Nuclear Power Plant
2015
A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model
eLife·2015· 63 citedOpen Access
Author response: A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model
2015Open Access
KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR
Nature Communications·2015· 54 citedOpen Access
Cellular and Molecular Mechanisms of Human B-Lymphocyte Differentiation
2015· 1 cited
Interleukin-6 Receptor and Signals
Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy·2015· 8 cited
Zinc-binding metallothioneins are key modulators of IL-4 production by basophils
Molecular Immunology·2015· 23 cited
Temporal Expression of Growth Factors Triggered by Epiregulin Regulates Inflammation Development
The Journal of Immunology·2015· 75 cited
112 A Experimental Study of Step by Step Measuring Method of Transfer Function of Structure
The Proceedings of Conference of Kansai Branch·2015
Inflammation Amplifier, a New Paradigm in Cancer Biology
Cancer Research·2013· 214 cited
The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance
Journal of Clinical Investigation·2013· 240 citedOpen Access
IL-6 and Inflammatory Diseases
2013· 8 cited
Disease-Association Analysis of an Inflammation-Related Feedback Loop
Cell Reports·2013· 2 citedOpen Access
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Frequent Co-authors

Masaaki Murakami(15), Tadamitsu Kishimoto(12), Toshiyuki Fukada(11), Keigo Nishida(9), Masahiko Hibi(8), Katsuhiko Ishihara(8), Tetsuya Taga(6), Satoru Yamasaki(5), Toru Atsumi(5), Daisuke Kamimura(5), Peter C. Heinrich(5), Tadashi Matsuda(4), Koichi Nakajima(4), Shintaro Hojyo(4), Thomas Geiger(4), Tilo Andus(4), Tsuneyasu Kaisho(4), Takuya Ohtani(4), Motoyuki Itoh(4), Bo Tang(3)