Mi Guo

Wenzhou Medical University — China

Medicine · Health Sciences

8h-index147citations23works3.32yr avg
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Research Topics

Traumatic Brain Injury and Neurovascular Disturbances(7), S100 Proteins and Annexins(5), Immune Response and Inflammation(3), NF-κB Signaling Pathways(3), Sepsis Diagnosis and Treatment(2)

Publications23 total

Discovery of <b>6l</b> with a New Skeleton of 6-Oxo- <i>N</i> -(4-(Quinolin-4-yloxy)phenyl)-1,6-dihydropyridine-3-carboxamide as a Dual-Action Inhibitor against JNK2 and the MKK7-JNK2 Protein–Protein Interaction for Acute Lung Injury
Journal of Medicinal Chemistry·2026
Discovery of <b>3g</b> as an Orally Bioavailable, TIR Domain Selective, and Potent MyD88 Inhibitor for the Treatment of Acute Lung Injury
Journal of Medicinal Chemistry·2025
Utility of Serum Occludin as a Prognostic Biomarker of Severe Traumatic Brain Injury and Mediation Role of Acute Lung Injury: A Two-Center Prospective Cohort Study
International Journal of General Medicine·2025· 2 citedOpen Access
Retraction notice to "Current knowledge of antisense long non-coding RNA in the occurrence and prognosis of skull base tumors" [Heliyon 10 (2024) e35960]
Heliyon·2025Open Access
Discovery of c-Kit as a New Therapeutic Target in LPS-Induced Acute Lung Injury through Novel Phenylamide Derivative D9
Journal of Medicinal Chemistry·2025· 3 cited
Anti-inflammatory agents design via the fragment hybrid strategy in the discovery of compound c1 for treating ALI and UC
European Journal of Medicinal Chemistry·2025· 3 cited
Discovery of Novel MyD88 Inhibitor A5S to Alleviate Acute Lung Injury with Favorable Drug-like Properties
Journal of Medicinal Chemistry·2024· 8 cited
Alteration of Serum MLKL Levels and Their Association with Severity and Clinical Outcomes in Human Severe Traumatic Brain Injury: A Prospective Cohort Study
International Journal of General Medicine·2024· 4 citedOpen Access
RETRACTED: Current knowledge of antisense long non-coding RNA in the occurrence and prognosis of skull base tumors
Heliyon·2024Open Access
Fragment-Based Anti-inflammatory Agent Design and Target Identification: Discovery of AF-45 as an IRAK4 Inhibitor to Treat Ulcerative Colitis and Acute Lung Injury
Journal of Medicinal Chemistry·2024· 9 citedOpen Access
Design, synthesis and bioactivity evaluation of 4-hydroxycoumarin derivatives as potential anti-inflammatory agents against acute lung injury and colitis
European Journal of Medicinal Chemistry·2024· 8 cited
Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice
European Journal of Medicinal Chemistry·2024· 6 cited
A Prediction Model for Prolonged Hospital Length of Stay (ProLOS) in Coronavirus Disease 2019 (COVID-19) Patients
Clinical Laboratory·2024
Discovery of the Diphenyl 6-Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the JNK2-NF-κB/MAPK Pathway
Journal of Medicinal Chemistry·2023· 22 citedOpen Access
Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis
European Journal of Medicinal Chemistry·2023· 18 cited
Prognostic Role of Serum Soluble Tim-3 in Severe Traumatic Brain Injury: A Prospective Observational Study
Neuropsychiatric Disease and Treatment·2023· 2 citedOpen Access
Serum hypoxia-inducible factor 1alpha emerges as a prognostic factor for severe traumatic brain injury
Clinica Chimica Acta·2021· 10 cited
Impact of serum omentin-1 concentrations on functional outcome among acute intracerebral hemorrhage patients
Clinica Chimica Acta·2020· 6 cited
Higher plasma C-type lectin-like receptor 2 concentrations for prediction of higher risk of 30-day mortality in isolated severe blunt traumatic brain injury
Clinica Chimica Acta·2019· 10 cited
A prospective study on serum secreted protein acidic and rich in cysteine-like 1 as a prognostic marker for severe traumatic brain injury
Clinica Chimica Acta·2019· 3 cited
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Frequent Co-authors

Qidong Tang(10), Qing-Wei Lv(8), Guang Liang(7), Liang-Jun Shen(6), Chenhui Sun(6), Young-Chang Cho(6), Ying Zhou(5), Zhiwei Zheng(5), Jing Zhou(5), Yu Zou(5), Won-Jea Cho(4), Hang-Bin Huang(4), Zhichao Chen(3), Songbin Yang(3), Chun-Song Yang(3), Xiaobo Li(3), Zhichao Chen(3), Pan Chen(3), Ke Dong(3), Miao Jiang(3)