Hyun‐Seok Hong

Yale University — United States

Medicine · Health Sciences

14h-index971citations27works3.02yr avg
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Research Topics

Alzheimer's disease research and treatments(12), Cholinesterase and Neurodegenerative Diseases(4), Rheumatoid Arthritis Research and Therapies(3), Computational Drug Discovery Methods(3), Natural Antidiabetic Agents Studies(3)

Publications27 total

Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development
International Journal of Molecular Sciences·2024· 4 citedOpen Access
Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development
Preprints.org·2024· 2 citedOpen Access
Genetic polymorphism in dopamine signaling modulates brain response to transcranial direct current stimulation
Neuroscience Applied·2023Open Access
Chest discomfort in a patient with dengue - is it an acute myocardial infarction?
PubMed·2018Open Access
Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer’s Disease
Journal of Medicinal Chemistry·2017· 37 citedOpen Access
Real-world experiences of folic acid supplementation (5 versus 30 mg/week) with methotrexate in rheumatoid arthritis patients: a comparison study
Reumatismo·2016· 5 citedOpen Access
A novel porcine model of Alzheimer"s disease based on lentivirus vector-mediated gene transfer
한국실험동물학회 학술발표대회 논문집·2016
3D Light-Sheet Fluorescence Microscopy of Cranial Neurons and Vasculature during Zebrafish Embryogenesis
Molecules and Cells·2015· 38 citedOpen Access
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE)
Bioorganic & Medicinal Chemistry·2015· 15 cited
Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90
Molecular Pharmacology·2015· 43 cited
Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation
Scientific Reports·2015· 62 citedOpen Access
Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier
Biochemical and Biophysical Research Communications·2013· 16 cited
Ligand-Based Design, Synthesis, and Biological Evaluation of 2-Aminopyrimidines, a Novel Series of Receptor for Advanced Glycation End Products (RAGE) Inhibitors
Journal of Medicinal Chemistry·2012· 58 citedOpen Access
A differential association of Apolipoprotein E isoforms with the amyloid‐β oligomer in solution
Proteins Structure Function and Bioinformatics·2010· 49 cited
FK506 Reduces Amyloid Plaque Burden and Induces MMP-9 in AβPP/PS1 Double Transgenic Mice
Journal of Alzheimer s Disease·2010· 52 cited
AMYLOID-PEPTIDE ACCELERATES ALTERATIONS OF EXPRESSION AND LOCALIZATION OF TIGHT JUNCTION PROTEINS VIA RAGE
Seoul National University Open Repository (Seoul National University)·2009
Acute Renal Failure in Coexisting IgA Nephropathy and Acute Interstitial Nephritis: Complete Recovery after Hemodialysis and Steroid Therapy
Kidney Research and Clinical Practice·2009Open Access
Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule <i>in vitro</i> and <i>in vivo</i>
Journal of Neurochemistry·2008· 69 citedOpen Access
P1‐450: Tomoregulin‐2 binds beta‐amyloid precursor protein and intracellular beta‐amyloid (Aβ)
Alzheimer s & Dementia·2008· 1 cited
P1‐420: Novel fluorene compounds bind A‐Beta amyloid aggregates and neutralize their toxicity
Alzheimer s & Dementia·2008Open Access
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Frequent Co-authors

Hee-Jin Ha(5), Lee‐Way Jin(4), Inhee Mook‐Jung(4), Duy H. Hua(4), Hee Yeon Kim(4), Jeewoo Lee(4), Young Ho Kim(4), Izumi Maezawa(3), Sandeep Rana(3), Young‐Ger Suh(3), R. Holland Cheng(2), Kit S. Lam(2), Aibin Shi(2), Lee‐Way Jin(2), Sung Min Son(2), Kwang‐Hyun Choi(2), Jiyoun Lee(2), Eun Ji Jeong(2), Kyoung Soo Kim(2), Ruiwu Liu(1)