Cheng‐Zhong Zhang

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index29.6kcitations215works4.22yr avg
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Research Topics

Cancer Genomics and Diagnostics(57), CRISPR and Genetic Engineering(27), Genomic variations and chromosomal abnormalities(24), Genetic factors in colorectal cancer(13), RNA modifications and cancer(13)

Publications160 total

Ionizing Radiation Shapes Genome Evolution Through Nuclear Abnormalities That Trigger Delayed Proliferative Death
2025Open Access
Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma
2025· 1 citedOpen Access
More Active Hair Growth in Human Scalp Psoriasis and Mouse Psoriasis: Evidence for the Same “Switch‐On” of Psoriasis and Hair Growth
International Journal of Dermatology·2025
MiR-223 within neutrophil axis promotes Th17 expansion by PI3K-AKT pathway in systemic lupus erythematosus
Arthritis Research & Therapy·2025· 2 citedOpen Access
Mechanisms of tandem duplication in the cancer genome
DNA repair·2024· 3 citedOpen Access
Successful Treatment of Mexiletine-Induced Methylprednisolone-Resistant DRESS Syndrome With TNF-α Inhibitor
American Journal of Therapeutics·2024
Hepatoprotective action mechanism and quantification of soyasaponin Bb in Abri Herba by HPLC and network pharmacology
Journal of Ethnopharmacology·2024· 8 citedOpen Access
A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
Cell·2024· 24 citedOpen Access
Chromosome breakage-replication/fusion enables rapid DNA amplification
2024· 4 citedOpen Access
Pharmacokinetic and oral bioavailability study of schaftoside in rats
Biomedical Chromatography·2024· 3 citedOpen Access
Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes
2024· 5 citedOpen Access
A case of mixed-type Henoch-Sch?nlein purpura manifesting as urticarial and annular purpuric lesions and IgA nephropathy
Chinese Journal of Dermatology·2024
Gooderoside A from Anoectochilus elatus attenuates acute and chronic pains by inhibiting NO/cGMP and IRAK4/IRAK1/TAK1 signaling pathways
Journal of Ethnopharmacology·2024· 4 cited
Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma
Nature Communications·2023· 27 citedOpen Access
Dissection of tumor-intrinsic and tumor-extrinsic features of MiT/TFE translocation renal cell carcinoma via single-cell RNA sequencing
The Oncologist·2023Open Access
A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma
2023· 3 citedOpen Access
Simultaneous determination of abrine, hypaphorine, schaftoside and soyasaponin Bb in rat plasma by UPLC–MS/MS and its application to a pharmacokinetic study after oral administration of <i>Abrus cantoniensis</i> Hance extract
Biomedical Chromatography·2023· 10 citedOpen Access
Heritable transcriptional defects from aberrations of nuclear architecture
Nature·2023· 79 citedOpen Access
Disseminated <i>Prototheca wickerhamii</i> infection in a patient with <i>CARD9</i> gene mutation
The Journal of Dermatology·2023· 5 citedOpen Access
Supplementary Table S2 from Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting
2023Open Access
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Frequent Co-authors

Jeremiah A. Wala(12), David Pellman(11), Matthew Meyerson(10), Chip Stewart(10), Rameen Beroukhim(9), Yilong Li(9), Marcin Imieliński(9), Kadir C. Akdemir(9), Steven E. Schumacher(8), Nicola D. Roberts(7), James E. Haber(7), Peter J. Campbell(7), Isidro Cortés‐Ciriano(7), Peter J. Park(7), Lars Feuerbach(6), Dmitry A. Gordenin(6), Leszek J. Klimczak(6), Jake June-Koo Lee(6), José M. C. Tubío(6), Lixing Yang(6)