Xuehua Pan

Peng Cheng Laboratory — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index260citations15works6.02yr avg
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Research Topics

Antibiotic Resistance in Bacteria(5), Antibiotics Pharmacokinetics and Efficacy(3), Advanced biosensing and bioanalysis techniques(2), Virus-based gene therapy research(2), Pneumonia and Respiratory Infections(2)

Publications15 total

NRBF2 homodimerization by its coiled-coil domain strengthens association with the PtdIns3K complex mediated by the MIT domain to promote autophagy
Autophagy·2025Open Access
Harnessing mRNA-encoded PcrV-targeting monoclonal antibodies for combating antibiotic-resistant P. aeruginosa infections
Molecular Therapy·2025Open Access
A review on Gaucher disease: therapeutic potential of β-glucocerebrosidase-targeted mRNA/saRNA approach
International Journal of Biological Sciences·2024· 18 citedOpen Access
The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs
Autophagy·2023· 2 citedOpen Access
Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa
npj Vaccines·2023· 67 citedOpen Access
The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression
Nature Communications·2023· 15 citedOpen Access
Development of a Library of Disulfide Bond-Containing Cationic Lipids for mRNA Delivery
Pharmaceutics·2023· 14 citedOpen Access
Designing multi-epitope mRNA construct as a universal influenza vaccine candidate for future epidemic/pandemic preparedness
International Journal of Biological Macromolecules·2022· 31 cited
<i>Tb</i> RAP1 has an unusual duplex DNA binding activity required for its telomere localization and VSG silencing
Science Advances·2020· 16 citedOpen Access
The hydrolytic water molecule of Class A β-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis
Scientific Reports·2020· 32 citedOpen Access
Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases
Antimicrobial Agents and Chemotherapy·2017· 16 citedOpen Access
Crystallographic Snapshots of Class A β-Lactamase Catalysis Reveal Structural Changes That Facilitate β-Lactam Hydrolysis
Journal of Biological Chemistry·2017· 24 citedOpen Access
Structural study of the active site of class A β-lactamase : mechanism of the catalytic process and its effect on antibiotic resistance
PolyU Institutional Research Archive (Hong Kong Polytechnic University)·2015
Perturbing the General Base Residue Glu166 in the Active Site of Class A β-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry·2014· 8 cited
Engineering Clostridia Neurotoxins with elevated catalytic activity
Toxicon·2013· 17 citedOpen Access

Frequent Co-authors

Yanxiang Zhao(9), Yunjiao He(7), Peng George Wang(5), Nino Rcheulishvili(4), Dimitri Papukashvili(3), Fengfei Xie(3), Ziqian Wang(3), Cong Liu(2), Jiao Zhao(2), Jinping Lei(2), Xuhui Huang(2), Yang Ji(2), Jiubiao Guo(2), Marjia Afrin(2), Amit Kumar Gaurav(2), Xian Yang(2), Bibo Li(2), Xianxiu Qiu(2), Shuai Wu(2), Xiaohua Li(2)