Wenbiao Chen

Chinese Academy of Sciences — China

Medicine · Health Sciences

29h-index4.9kcitations84works2.02yr avg
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Research Topics

Pancreatic function and diabetes(35), CRISPR and Genetic Engineering(21), Zebrafish Biomedical Research Applications(15), Diabetes and associated disorders(10), Animal Genetics and Reproduction(10)

Publications84 total

Ppid is necessary for overnutrition-induced β-cell loss
American Journal of Physiology-Endocrinology and Metabolism·2025Open Access
Liver-Derived C18/22/24 Ceramides Disturb Pancreatic β Cell Homeostasis Under FoxO1-Targeting Hypoglycemic Intervention
SSRN Electronic Journal·2025Open Access
Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways
iScience·2024· 3 citedOpen Access
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
Molecular Metabolism·2024· 3 citedOpen Access
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
2024Open Access
Plaat1l1 controls feeding induced NAPE biosynthesis and contributes to energy balance regulation in zebrafish
Prostaglandins & Other Lipid Mediators·2024· 2 citedOpen Access
ErbB3 is required for hyperaminoacidemia-induced pancreatic α cell hyperplasia
Journal of Biological Chemistry·2024· 5 citedOpen Access
Animal Models for Understanding the Mechanisms of Beta Cell Death during Type 2 Diabetes Pathogenesis
Biomedicines·2024· 7 citedOpen Access
Plaat1l1 controls feeding induced NAPE biosynthesis and contributes to energy balance regulation in zebrafish
2024Open Access
Plaat1l1 Controls Feeding Induced Nape Biosynthesis and Contributes to Energy Balance Regulation in Zebrafish
SSRN Electronic Journal·2024Open Access
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2
2023· 10 citedOpen Access
Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 System
Fishes·2023· 14 citedOpen Access
Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between the mTORC1 and CaSR-Gq signaling pathways
Nature Communications·2023· 23 citedOpen Access
Optimized protocol for live imaging of overnutrition-elicited interactions between immune cells and β cells in zebrafish
STAR Protocols·2023Open Access
Insulin secretion assays in an engineered MIN6 cell line
MethodsX·2023· 4 citedOpen Access
Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatus
Marine Biotechnology·2022· 23 cited
Macrophages and neutrophils are necessary for ER stress-induced β cell loss
Cell Reports·2022· 28 citedOpen Access
Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion
Molecular Metabolism·2022· 5 citedOpen Access
Decision letter: A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
2022Open Access
Editor's evaluation: A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
2022Open Access
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Frequent Co-authors

Lisette A. Maddison(14), Mingyu Li(9), Alvin C. Powers(8), Patrick Page-McCaw(8), E. Danielle Dean(7), Linlin Yin(6), Chunhua Dai(6), Bingyuan Yang(6), Brittney A. Covington(6), Roger D. Cone(5), Zihan Tang(5), Shawn M. Burgess(4), Maximilian Michel(4), Yue Zhang(4), Adam Amsterdam(3), Nancy Hopkins(3), Bensheng Ju(3), Liqing Zang(3), Jianjun Lu(3), Ahmed Elaswad(3)