Leslie A. Lange

Translational Genomics Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

64h-index23.9kcitations301works1.22yr avg
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Research Topics

Genetic Associations and Epidemiology(93), Nutrition, Genetics, and Disease(19), Prostate Cancer Treatment and Research(18), Cancer Cells and Metastasis(16), Obesity, Physical Activity, Diet(13)

Publications285 total

Mechanistic Link Between Glyoxalase 1 Expression and Methylglyoxal-Induced Oncogenic Stress in Prostate Cancer
2025Open Access
Androgen receptor contributes to radioresistance through DNA repair and autophagy in AR-positive prostate cancer cells
2025Open Access
The TIDIER Trial: A randomized, phase II clinical trial of time-restricted eating versus nutritional counseling among patients receiving radiation or chemoradiation for prostate, cervical or rectal cancer
2025Open Access
[Construction and validation of acute pulmonary embolism diagnostic model based on clinical and laboratory indicators].
PubMed·2025
Improving performance of polygenic risk scores for hypertension across two ancestry groups
2025Open Access
Machine learning‐based clustering identifies obesity subgroups with differential multi‐omics profiles and metabolic patterns
UNC Libraries·2025Open Access
Exploiting AR-Synergistic Metabolic Vulnerabilities in Prostate Cancer
Cancer Research·2025
ACR Appropriateness Criteria® Staging and Disease Monitoring of Colon Cancer and Appendiceal Cancer
Journal of the American College of Radiology·2025
ACR Appropriateness Criteria® Staging and Disease Monitoring of Rectal Cancer
Journal of the American College of Radiology·2025
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
UNC Libraries·2025Open Access
Utility of metastasis-directed radiotherapy with and without hormonal therapy in management of oligometastatic prostate cancer
JNCI Cancer Spectrum·2025Open Access
Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program
Diabetes·2025
CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway
International Journal of Molecular Sciences·2025Open Access
Quantitative magnetic resonance imaging to differentiate clinically significant tumor from other tissues in the prostate
International Journal of Radiation Oncology*Biology*Physics·2025
Clinical Outcomes of Biology-Guided Radiation Therapy for Osseous Metastases
International Journal of Radiation Oncology*Biology*Physics·2025Open Access
Comparison of Perceptions of Barriers to Advancement for Women in Radiation Oncology among Different Practice Settings
International Journal of Radiation Oncology*Biology*Physics·2025
CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway
Preprints.org·2025Open Access
Abstract P3-10-30: Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
Clinical Cancer Research·2025
Data from Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage
2025Open Access
Supplementary Figure 2 from Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage
2025Open Access
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Frequent Co-authors

Brendan J. Keating(13), Yiran Guo(11), Myriam Fornage(11), James G. Wilson(11), Mingyao Li(8), Matthew B. Lanktree(8), Håkon Håkonarson(8), Alexander P. Reiner(8), Guillaume Lettre(8), Sandosh Padmanabhan(7), Erik P.A. van Iperen(7), L. Adrienne Cupples(7), Santhi K. Ganesh(7), Toby Johnson(6), Xiuqing Guo(6), Fotios Drenos(6), N. Charlotte Onland‐Moret(6), George Davey Smith(6), Susan Redline(6), Meena Kumari(6)