Manish K. Jain

Northwestern University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index1.2kcitations39works19.72yr avg
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Research Topics

Receptor Mechanisms and Signaling(14), Neuroscience and Neuropharmacology Research(7), Pharmacological Receptor Mechanisms and Effects(5), Biochemical Analysis and Sensing Techniques(4), Crystallization and Solubility Studies(4)

Publications39 total

EPS2.03Highly-effective CFTR modulation and lung development by age, gender, and height among children with cystic fibrosis
Journal of Cystic Fibrosis·2025
Functionally Selective Dopamine D1 Receptor Endocytosis and Signaling by Catechol and Noncatechol Agonists
Biochemistry·2025
The structural diversity of psychedelic drug actions revealed
Nature Communications·2025· 24 citedOpen Access
Bitter taste receptor activation by cholesterol and an intracellular tastant
UNC Libraries·2024Open Access
Author Correction: Bitter taste receptor activation by cholesterol and an intracellular tastant
UNC Libraries·2024Open Access
EPS10.06 Highly-effective CFTR modulation is associated with greater height and peak lung function in children with cystic fibrosis
Journal of Cystic Fibrosis·2024
Author Correction: Bitter taste receptor activation by cholesterol and an intracellular tastant
Nature·2024· 3 citedOpen Access
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
UNC Libraries·2024· 2 citedOpen Access
AlphaFold2 structures guide prospective ligand discovery
Science·2024· 116 citedOpen Access
Functionally selective dopamine D1 receptor endocytosis and signaling by catechol and non-catechol agonists
2024· 1 citedOpen Access
Bitter taste receptor activation by cholesterol and an intracellular tastant
Nature·2024· 71 cited
AlphaFold2 structures template ligand discovery
2023· 18 citedOpen Access
Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity
2023· 3 citedOpen Access
Modulation of the conformation, fibrillation, and fibril morphologies of human brain α-, β-, and γ-synuclein proteins by the disaccharide chemical chaperone trehalose
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2023
Structures of the entire human opioid receptor family
Cell·2023· 170 citedOpen Access
CCDC 2093770: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2093535: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2093536: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2093534: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
Nature·2022· 240 citedOpen Access
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Frequent Co-authors

Bryan L. Roth(18), Jeffrey F. DiBerto(10), Kuglae Kim(8), Ximena Barros-Álvarez(8), John J. Irwin(8), Brian K. Shoichet(8), Daniel E. Felsing(8), Samuel T. Slocum(7), Georgios Skiniotis(7), Ryan H. Gumpper(7), John Allen(7), Yongfeng Liu(6), Xi‐Ping Huang(6), Anat Levit(6), Danielle N. Confair(6), Oh Sang Kweon(6), David N. Kamber(6), James P. Phelan(6), Luan Carvalho Martins(6), Alpay B. Seven(6)