Xianghong Kuang

The University of Texas MD Anderson Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index773citations30works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(7), Endoplasmic Reticulum Stress and Disease(5), HIV Research and Treatment(3), Cancer-related Molecular Pathways(3), Autophagy in Disease and Therapy(3)

Publications30 total

USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity
PLoS ONE·2024Open Access
USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity
2022Open Access
Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice
Cancers·2021· 7 citedOpen Access
Abstract 2129: Usp22 controls multiple signaling pathways in development and disease
Cancer Research·2021
Oncogenic Functions of the SAGA Complex
The FASEB Journal·2021
USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta
Development·2019· 47 cited
ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth
Molecular Cell·2016· 141 citedOpen Access
Gcn5 and PCAF Regulate <i>PPAR</i>γ and <i>Prdm16</i> Expression To Facilitate Brown Adipogenesis
Molecular and Cellular Biology·2014· 64 citedOpen Access
Activation of AMP-activated protein kinase in cerebella of Atm−/− mice is attributable to accumulation of reactive oxygen species
Biochemical and Biophysical Research Communications·2012· 22 citedOpen Access
Oxidative stress-mediated neurodegeneration: A tale of two models
2011· 4 cited
Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected mice
Neurochemistry International·2010· 16 cited
Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes
Neurochemistry International·2010· 18 citedOpen Access
Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice
Brain Research·2009· 46 cited
Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm−/− mice
Biochemical and Biophysical Research Communications·2009· 11 cited
The drug monosodium luminol (GVT) preserves crypt-villus epithelial organization and allows survival of intestinal T cells in mice infected with the ts1 retrovirus
Immunology Letters·2009· 15 cited
The drug monosodium luminol (GVT®) preserves thymic epithelial cell cytoarchitecture and allows thymocyte survival in mice infected with the T cell-tropic, cytopathic retrovirus ts1
Immunology Letters·2009· 9 cited
The mammalian target of rapamycin (mTOR) signaling in thymic lymphomagenesis in Atm-/- mice
Clinical Cancer Research·2008
Endoplasmic Reticulum Stress and Unfolded Protein Response in Atm-Deficient Thymocytes and Thymic Lymphoma Cells Are Attributable to Oxidative Stress
Neoplasia·2008· 27 citedOpen Access
Interleukin‐10 gene promoter polymorphisms and the risk of nasopharyngeal carcinoma
Tissue Antigens·2007· 45 cited
The glucorcorticoid receptor is increased in Atm−/− thymocytes and in Atm−/− thymic lymphoma cells, and its nuclear translocation counteracts c-myc expression
Steroids·2007· 6 cited
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Frequent Co-authors

P.K.Y. Wong(18), Mingshan Yan(13), Virginia L. Scofield(10), Sharon Dent(8), Evangelia Koutelou(7), Wenan Qiang(7), William S. Lynn(7), Jianjun Shen(7), George Stoica(5), Andrew P. Salinger(4), Boyko S. Atanassov(3), Yue Lu(3), Kevin Lin(3), Na Liu(3), Li Wang(2), Dean G. Tang(2), Jodi M Cahill(2), Jinrong Liu(2), Amy J. Reid(2), Weibo Liang(2)