Melitta Schachner

Rutgers, The State University of New Jersey — United States

Neuroscience · Life Sciences

72h-index17.1kcitations252works0.52yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(80), Neurogenesis and neuroplasticity mechanisms(73), Nerve injury and regeneration(39), Neuroinflammation and Neurodegeneration Mechanisms(33), Axon Guidance and Neuronal Signaling(30)

Publications252 total

Loss of B3GAT1/HNK-1 disrupts glioma-CD8+ T cell immune synapse formation for immune escape
International Immunopharmacology·2025
Consequences of Adhesion Molecule Close Homolog of L1 Deficiency for Neurons and Glial Cells in the Mouse Spinal Cord After Injury
Biomolecules·2025Open Access
NCAM2 promotes targeting of APP from the cell surface to BACE1-containing recycling endosomes
Progress in Neurobiology·2025Open Access
The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy
Biomolecules·2025Open Access
L1CAM mimetic compound duloxetine improves cognitive impairment in 5xFAD mice and protects Aβ1-42-damaged HT22 cells
European Journal of Pharmacology·2025· 1 cited
Functional Relationships between L1CAM, LC3, ATG12, and Aβ
International Journal of Molecular Sciences·2024· 2 citedOpen Access
The composition of motor recovery revealed by syllable-level behavioral analysis after spinal cord injury
2023· 3 citedOpen Access
Interaction of L1CAM with LC3 Is Required for L1-Dependent Neurite Outgrowth and Neuronal Survival
International Journal of Molecular Sciences·2023· 6 citedOpen Access
The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions
International Journal of Molecular Sciences·2023· 9 citedOpen Access
The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomes
Cellular and Molecular Life Sciences·2022· 4 citedOpen Access
Close Homolog of L1 Modulates Area-Specific Neuronal Positioning and Dendrite Orientation in the Cerebral Cortex
UNC Libraries·2021Open Access
The Cytoplasmic Domain of the Large Myelin-Associated Glycoprotein Isoform Is Needed for Proper CNS But Not Peripheral Nervous System Myelination
UNC Libraries·2021· 8 citedOpen Access
Close Homolog of L1 and Neuropilin 1 Mediate Guidance of Thalamocortical Axons at the Ventral Telencephalon
UNC Libraries·2021Open Access
Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity
UNC Libraries·2020Open Access
L1 and CHL1 Cooperate in Thalamocortical Axon Targeting
UNC Libraries·2020· 1 citedOpen Access
Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse
UNC Libraries·2020Open Access
Adhesion Molecule L1 Agonist Mimetics Protect Against the Pesticide Paraquat-Induced Locomotor Deficits and Biochemical Alterations in Zebrafish
Frontiers in Neuroscience·2020· 20 citedOpen Access
Hyperfunction of the stress response system and novelty‐induced hyperactivity correlate with enhanced cocaine‐induced conditioned place preference in NCAM‐deficient mice
Addiction Biology·2020· 9 citedOpen Access
<i>L1cam</i> Curbs the Differentiation of Adult-Born Hippocampal Neurons
SSRN Electronic Journal·2020Open Access
NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesis
The Journal of Cell Biology·2019· 25 citedOpen Access
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Frequent Co-authors

Alexander Dityatev(14), Olena Bukalo(6), Hans Welzl(6), Udo Bartsch(5), Helmut Kettenmann(5), Harold Cremer(4), Rudolf Martini(4), Rita Gerardy‐Schahn(4), Thomas Becker(3), Catherina G. Becker(3), Dirk Montag(3), Vladimir Sytnyk(3), Iryna Leshchyns’ka(3), Oleg Senkov(3), Kurt H. Backus(3), Oliver Stork(3), Jürgen Zielasek(2), Klaus V. Toyka(2), Alain Artola(2), Gaga Kochlamazashvili(2)