Gregg Fields

Florida Atlantic University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index8.6kcitations154works0.82yr avg
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Research Topics

Protease and Inhibitor Mechanisms(64), Chemical Synthesis and Analysis(38), Peptidase Inhibition and Analysis(38), Cell Adhesion Molecules Research(37), Collagen: Extraction and Characterization(21)

Publications153 total

Matrix metalloproteinase 13 (MMP-13) processing of type II collagen is altered by antibodies and citrullination found in the early stages of rheumatoid arthritis
Matrix Biology·2025· 1 cited
Heat inactivation of proteins: implications for the Mars Sample Campaign and other extraterrestrial sample return missions
International Journal of Astrobiology·2025· 1 citedOpen Access
Novel Insights into the Catalytic Mechanism of Collagenolysis by Zn(II)-Dependent Matrix Metalloproteinase-1
Biochemistry·2024· 2 citedOpen Access
Editorial ‐ FAU research on Alzheimer's disease
Journal of Cellular Physiology·2024
Gelatinases are important for CD4+ T-cell metabolic reprogramming
The Journal of Immunology·2024
Identification of binding partners that facilitate membrane‐type 5 matrix metalloproteinase (MT5‐MMP) processing of amyloid precursor protein
Journal of Cellular Physiology·2024· 1 citedOpen Access
Analysis of Matrix Metalloproteinase Activity and Inhibition in Cancer Spheroids
Methods in molecular biology·2023· 1 cited
Catalytic Mechanism of Collagen Hydrolysis by Zinc(II)-Dependent Matrix Metalloproteinase-1
The Journal of Physical Chemistry B·2023· 11 citedOpen Access
A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Nature Communications·2023· 12 citedOpen Access
Abstract 2757: Combination of a fluorescent substrate-based MMP activity assay and hit pick reading/imaging procedure to screen for inhibitors of MT1-MMP activity and 3D glioma tumoroid invasion
Cancer Research·2023· 1 cited
Supplementary Data from Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma–Induced Osteolysis and Reduces Overall Survival
2023Open Access
Data from Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma–Induced Osteolysis and Reduces Overall Survival
2023Open Access
Data from Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma–Induced Osteolysis and Reduces Overall Survival
2023Open Access
Front Cover: Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase‐1 (ChemPhysChem 3/2023)
ChemPhysChem·2023Open Access
Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase‐1
ChemPhysChem·2023Open Access
Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage
Arthritis Research & Therapy·2022· 14 citedOpen Access
Development of a putative Zn2+-chelating but highly selective MMP-13 inhibitor
Bioorganic & Medicinal Chemistry Letters·2022· 10 citedOpen Access
Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase‐1
ChemPhysChem·2022· 9 cited
Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst
Molecular Biomedicine·2022· 3 citedOpen Access
Application of a triple‐helical peptide inhibitor of <scp>MMP</scp>‐2/<scp>MMP</scp>‐9 to examine T‐cell activation in experimental autoimmune encephalomyelitis
Peptide Science·2022Open Access
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Frequent Co-authors

Janelle L. Lauer‐Fields(7), Cynthia G. Fields(7), Roma Stawikowska(6), Andrew Miles(5), Ying‐Ching Yu(4), Leo T. Furcht(4), Navdeep B. Malkar(4), Matthew Tirrell(3), Janelle Lauer(3), Henning Birkedal‐Hansen(3), Harold E. Van Wart(3), James B. McCarthy(3), Rita Fuerst(3), William Roush(3), Dorota Tokmina‐Roszyk(3), Tatyana G. Karabencheva‐Christova(3), Richard L. Noble(2), B. Grab(2), Sarah Netzel–Arnett(2), Amy P.N. Skubitz(2)