Ann G. Hayes

Neuroscience · Life Sciences

31h-index2.9kcitations76works0.02yr avg
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Research Topics

Neuropeptides and Animal Physiology(37), Pharmacological Receptor Mechanisms and Effects(28), Receptor Mechanisms and Signaling(22), Pain Mechanisms and Treatments(18), Neuroscience and Neuropharmacology Research(9)

Publications76 total

THuNDRous news for human dopamine researchers: A selective dopamine D1 receptor antagonist will soon be available for clinical research
Journal of Psychopharmacology·2018· 4 citedOpen Access
Multi-parameter lead optimization to give an oral CHK1 inhibitor clinical candidate: (R)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)
2015
The European College of Neuropsychopharmacology (ECNP) Medicines Chest Initiative: Rationale and Promise
Pharmaceutical Medicine·2015· 3 cited
Key role of publication of clinical data for target validation
Pharmacology Research & Perspectives·2015· 4 citedOpen Access
The extinction of drugs for clinical research: Can the ECNP medicines chest save them?
European Neuropsychopharmacology·2014· 6 citedOpen Access
Multiple mechanisms have been tested in pain—how can we improve the chances of success?
Current Opinion in Pharmacology·2013· 22 cited
Why is publication of negative clinical trial data important?
British Journal of Pharmacology·2012· 20 citedOpen Access
MULTISITE RESEARCH
Gastroenterology Nursing·2011· 4 cited
ChemInform Abstract: Novel 1,2,4‐Oxadiazoles as Potent and Selective Histamine H3 Receptor Antagonists.
ChemInform·1996
ChemInform Abstract: Novel 6‐Substituted 2‐Aminotetralins with Potent and Selective Affinity for the Dopamine D3 Receptor.
ChemInform·1996
Novel 1, 2, 4-oxadiazoles as potent and selective histamine H3 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·1996· 106 cited
A Puzzling Accidental Intraoperative Finding
Anesthesia & Analgesia·1996
Novel 6-substituted 2-aminotetralins with potent and selective affinity for the dopamine D3 receptor
Bioorganic & Medicinal Chemistry Letters·1996· 29 cited
ChemInform Abstract: A Novel Series of Arylpiperazines with High Affinity and Selectivity for the Dopamine D3 Receptor.
ChemInform·1995
A novel series of arylpiperazines with high affinity and selectivity for the dopamine D3 receptor
Bioorganic & Medicinal Chemistry Letters·1995· 49 cited
ChemInform Abstract: 4‐((Alkylamino)methyl)furo(3,2‐c)pyridines: A New Series of Selective . kappa.‐Receptor Agonists.
ChemInform·1994
ChemInform Abstract: A Potent New Class of ‐Receptor Agonist: 4‐Substituted 1‐(Arylacetyl)‐ 2‐((dialkylamino)methyl)piperazines.
ChemInform·1994
4-[(Alkylamino)methyl]furo[3,2-c]pyridines: A New Series of Selective .kappa.-Receptor Agonists
Journal of Medicinal Chemistry·1994· 35 citedOpen Access
Acute and chronic behavioural sequelae resulting from intrastriatal injection of an NMDA agonist
Pharmacology Biochemistry and Behavior·1994· 6 cited
Reply
Journal of the American Academy of Dermatology·1993Open Access
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Frequent Co-authors

M.B. Tyers(17), P.J. Birch(13), Michael J. Sheehan(12), M. Skingle(11), D. I. C. SCOPES(10), Michael B. Tyers(8), Alan Naylor(5), Duncan B. Judd(5), Carol J. Grossman(4), H. L. Rogers(4), Jane E. Lloyd(3), S. P. Close(3), Peter J. Elliott(3), A.S. Marriott(3), Susan M. Harrison(2), Philip J. Birch(2), Neil J. Hayward(2), Delia M. Walsh(2), Peter Murray(2), Martin R. Johnson(2)