Namkyu Lee

Sejong University — South Korea

Medicine · Health Sciences

13h-index640citations32works0.02yr avg
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Research Topics

Cytomegalovirus and herpesvirus research(9), Herpesvirus Infections and Treatments(8), HIV/AIDS drug development and treatment(5), Viral-associated cancers and disorders(5), Carbohydrate Chemistry and Synthesis(4)

Publications32 total

Analysis of usage patterns and probabilistic risk assessment of personal care products in Korea
Food and Chemical Toxicology·2022· 2 cited
Hypoxic induction of apoptosis occurs through HIF-1α and accompanies mammalian sterile 20-like kinase 2 cleavage in human endometrial adenocarcinoma Ishikawa cells
Biochemical and Biophysical Research Communications·2022· 6 cited
Human mesenchymal stem cells primed with a novel compound CND-E enhance the suppression of microglial activation in vitro
Cytotherapy·2017
General Pharmacology of the New Antiviral Agent SK 1899
Arzneimittelforschung·2011
Structure-related cytotoxicity and anti-hepatofibric effect of asiatic acid derivatives in rat hepatic stellate cell-line, HSC-T6
Archives of Pharmacal Research·2004· 40 cited
Recent Advances in Topoisomerase I-Targeting Agents, Camptothecin Analogues
Mini-Reviews in Medicinal Chemistry·2002· 37 cited
Synthesis and phosphodiesterase inhibitory activity of new sildenafil analogues containing a carboxylic acid group in the 5′-sulfonamide moiety of a phenyl ring
Bioorganic & Medicinal Chemistry·2001· 49 cited
ChemInform Abstract: Synthesis and Biological Evaluation of Novel A‐Ring Modified Hexacyclic Camptothecin Analogues.
ChemInform·2001
Synthesis and phosphodiesterase 5 inhibitory activity of new 5-phenyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one derivatives containing an N-acylamido group on a phenyl ring
Bioorganic & Medicinal Chemistry·2001· 29 cited
Pharmacokinetic studies of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an oral prodrug for the antiviral agent penciclovir.
PubMed·2001· 1 cited
ChemInform Abstract: Synthesis of 5‐[2‐(Guanin‐9‐yl)‐ and 5‐[2‐(2‐Aminopurin‐9‐yl)ethyl] ‐2‐D‐ribo‐(1′,2′,3′,4′‐tetrahydroxybutyl)‐1,3‐dioxane.
ChemInform·2001
Synthesis and phosphodiesterase 5 inhibitory activity of novel phenyl ring modified sildenafil analogues
Bioorganic & Medicinal Chemistry·2001· 23 cited
Synthesis and Biological Evaluation of Novel A-Ring Modified Hexacyclic Camptothecin Analogues
Journal of Medicinal Chemistry·2001· 78 citedOpen Access
ChemInform Abstract: Synthesis of 9‐[2‐(2‐Hydroxymethyl)‐2‐methyl‐, ‐(2‐Acetoxymethyl)‐2‐methyl‐, ‐(2,2‐Di(hydroxymethyl)‐, and ‐(2,2‐Di(acetoxymethyl)‐1,3‐dioxan‐5‐yl)ethyl] Derivatives of Guanine and 2‐Aminopurine.
ChemInform·2001
Synthesis of 5‐[2‐(guanin‐9‐yl)‐ and 5‐[2‐(2‐aminopurin‐9‐yl)ethyl]‐2‐D‐<i>ribo</i>‐(1,2′,3′,4′‐tetrahydroxybutyl)‐1,3‐dioxane
Journal of Heterocyclic Chemistry·2001· 4 cited
Synthesis of 9‐[2‐(2‐hydroxymethyl‐2‐methyl‐, ‐(2‐acetoxymethyl‐2‐methyl‐, ‐(2,2‐di(hydroxymethyl)‐, and ‐(2,2‐Di(acetoxymethyl)‐1,3‐dioxan‐5‐yl)ethyl] derivatives of guanine and 2‐aminopurine
Journal of Heterocyclic Chemistry·2000· 2 cited
Enantioselective Enolate Protonation with Chiral Anilines:  Scope, Structural Requirements, and Mechanistic Implications
Journal of the American Chemical Society·2000· 44 cited
Synthesis and evaluation of 2-Amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-Amino-9-(3-alkoxycarbonyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines as potential prodrugs of penciclovir
Bioorganic & Medicinal Chemistry·1999· 11 cited
ChemInform Abstract: Synthesis and Evaluation of 2‐Amino‐9‐(1,3‐dihydroxy‐2‐propoxymethyl)‐6‐fluoropurine Mono‐ and Diesters as Potential Prodrugs of Ganciclovir.
ChemInform·1999
Synthesis of carbon‐14 labelled 2‐amino‐9‐(3‐hydroxymethyl‐4‐isopropoxycarbonyloxybut‐1‐yl)purine (SK1875), a potential prodrug of penciclovir
Journal of Labelled Compounds and Radiopharmaceuticals·1999· 1 cited
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Frequent Co-authors

Kieyoung Chang(13), Key H. Kim(10), Dae-Kee Kim(9), Guang-Jin Im(9), Dae‐Kee Kim(8), Do Hyun Ryu(7), Won-Son Choi(7), Jae-Sun Kim(6), Dae‐Kee Kim(6), Young Woo Kim(5), Edwin Vedējs(4), Guang‐Jin Im(4), In‐Ho Jung(4), Young‐Woo Kim(4), Hun‐Taek Kim(4), Ju Young Lee(3), Young‐Woo Kim(3), Jae‐Sun Kim(3), Won‐Son Choi(3), Sukho Lee(3)