Stuart McLaren

Wellcome Sanger Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index45.2kcitations50works0.02yr avg
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Research Topics

Cancer Genomics and Diagnostics(18), Genomics and Chromatin Dynamics(7), Chromosomal and Genetic Variations(6), Genomic variations and chromosomal abnormalities(6), Chromatin Remodeling and Cancer(5)

Publications46 total

Abstract 3555: COSMIC: two decades of curating somatic variants in cancer
Cancer Research·2024
COSMIC: a curated database of somatic variants and clinical data for cancer
Nucleic Acids Research·2023· 444 citedOpen Access
Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nature·2019· 18 citedOpen Access
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
Nature Genetics·2018· 232 citedOpen Access
Genomic Classification and Prognosis in Acute Myeloid Leukemia
New England Journal of Medicine·2016· 4.2k citedOpen Access
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nature·2016· 2.3k citedOpen Access
The Life History of 21 Breast Cancers
Cell·2015· 9 citedOpen Access
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
Nature Medicine·2015· 816 citedOpen Access
Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
Nature Genetics·2015· 18 citedOpen Access
High burden and pervasive positive selection of somatic mutations in normal human skin
Science·2015· 1.8k citedOpen Access
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
Nature Genetics·2015· 449 citedOpen Access
Polygenic in vivovalidation of cancer mutations using transposons
Genome biology·2014· 6 citedOpen Access
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
Science·2014· 424 citedOpen Access
Erratum: Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
Nature Genetics·2014· 3 citedOpen Access
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
Nature Communications·2014· 890 citedOpen Access
Erratum: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome
Nature·2013· 29 citedOpen Access
Somatic <i>CALR</i> Mutations in Myeloproliferative Neoplasms with Nonmutated <i>JAK2</i>
New England Journal of Medicine·2013· 1.7k citedOpen Access
Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution
Blood·2013
The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients
Blood·2013· 2 cited
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
Nature Genetics·2013· 836 citedOpen Access
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Frequent Co-authors

Jon W. Teague(28), Peter J. Campbell(24), Peter Van Loo(23), Keiran Raine(23), P. Andrew Futreal(23), Adam P. Butler(21), Michael R. Stratton(21), David C. Wedge(21), Serena Nik‐Zainal(19), Andrew Menzies(19), David Jones(18), Laura Mudie(16), Patrick Tarpey(15), Lucy Stebbings(14), Helen Davies(14), Sancha Martin(14), Ludmil B. Alexandrov(12), Gunes Gundem(11), Graham R. Bignell(11), Sarah O’Meara(11)