Masayuki Kanai

Daiichi Sankyo (United States) — United States

Medicine · Health Sciences

17h-index1.8kcitations37works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(9), Neuropeptides and Animal Physiology(9), DNA Repair Mechanisms(8), PARP inhibition in cancer therapy(7), Microtubule and mitosis dynamics(6)

Publications37 total

HERTHENA-Lung01: A Phase II Study of Patritumab Deruxtecan (HER3-DXd) in Previously Treated Metastatic <i>EGFR</i> -mutated NSCLC
Future Oncology·2023· 22 cited
An open-label, phase II study of patritumab deruxtecan (HER3-DXd, U3-1402) in patients (pts) with previously treated advanced/metastatic colorectal cancer (CRC).
Journal of Clinical Oncology·2021· 4 cited
Method of Calculation of Priority in Nodule Detection CAD Algorithm for CT Lung Cancer Screening
IEICE Technical Report; IEICE Tech. Rep.·2018
Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma
Journal of Hepatology·2016· 31 cited
An interconnected hierarchical model of cell death regulation by the BCL-2 family
Nature Cell Biology·2015· 245 citedOpen Access
Abstract 4456: Aurora-A is a downstream target of RAS and forms a positive feedback regulation loop with NF-κB in non-small cell lung cancer
Cancer Research·2014
Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
Molecular Cell·2014· 440 citedOpen Access
Abstract 515: Aurora-A is a determinant of tamoxifen resistance by phosphorylation and activation of ERα in breast cancer.
Cancer Research·2013
Mortalin: A Positive Regulator of Centrosome Duplication and Amplification
2012
Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity
Molecular biology intelligence unit·2008· 4 cited
Inhibition of Crm1–p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation
Nature Cell Biology·2007· 201 cited
Physical and functional interaction between mortalin and Mps1 kinase
Genes to Cells·2007· 56 citedOpen Access
Haploinsufficiency of poly(ADP-ribose) polymerase-1-mediated poly(ADP-ribosyl)ation for centrosome duplication
Biochemical and Biophysical Research Communications·2007· 17 cited
ポリ(ADP-リボシル)化によるCrm1-p53相互作用阻害とp53核輸出阻害 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター
Nature Cell Biology·2007
ポリ(ADP‐リボシル)化によるCrm1‐p53相互作用阻害とp53核輸出阻害
Nature Cell Biology·2007
Interaction between ROCK II and Nucleophosmin/B23 in the Regulation of Centrosome Duplication
Molecular and Cellular Biology·2006· 92 citedOpen Access
Centrosome amplification in adult T‐cell leukemia and human T‐cell leukemia virus type 1 Tax‐induced human T cells
Cancer Science·2006· 37 citedOpen Access
Suppression of Centrosome Amplification after DNA Damage Depends on p27 Accumulation
Cancer Research·2006· 45 citedOpen Access
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in <i>Drosophila melanogaster</i>
Proceedings of the National Academy of Sciences·2003· 194 citedOpen Access
Enhanced expression of MYCN leads to centrosome hyperamplification after DNA damage in neuroblastoma cells
Oncogene·2003· 22 cited
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Frequent Co-authors

Kayoko Iwao(12), Masanao Miwa(10), Ken Kitamura(10), Tetsuo Oka(10), Kenji Fukasawa(8), Kazuhito Akahori(8), Takao Taniguchi(7), Masanobu Yoshikawa(7), Shuji Hanai(5), Tomomi Kobayashi(5), Song‐Hee Kim(4), Eiji Sugihara(4), Kazuhiko Uchida(4), Masaru Nakabayashi(4), Kazuhiko Hanashiro(3), Shigeru Takahashi(3), Emily H. Cheng(2), Sayaka Ohashi(2), Wei‐Min Tong(2), Zhao‐Qi Wang(2)