Seiga Itoh

Kyowa Kirin (Japan) — Japan

Medicine · Health Sciences

22h-index2.2kcitations61works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(9), Viral Infectious Diseases and Gene Expression in Insects(8), Immune Response and Inflammation(7), Bacterial Genetics and Biotechnology(6), RNA and protein synthesis mechanisms(6)

Publications61 total

Production of recombinant granulocyte colony-stimulating factor by knocking into the active immunoglobulin heavy chain gene locus in the hybridoma cell line
Cytotechnology·2001
Purification and Characterization of Recombinant Human Granulocyte Colony-Stimulating Factor (rhG-CSF) Derivatives: KW-2228 and Other Derivatives
Bioscience Biotechnology and Biochemistry·1998· 15 citedOpen Access
KJ1 Development of Neu-up, a Human G-CSF Derivative with Higher Specific Activity :
日本生物工学会大会講演要旨集·1997
Structure of KW‐2228, a tailored human granulocyte colony‐ stimulating factor with enhanced biological activity and stability
FEBS Letters·1997· 11 citedOpen Access
Efficient expression of pro-urokinase by human lymphoblastoid Namalwa KJM-1 cells using Moloney retroviral promoter
Cytotechnology·1996
Development of Neu-up (KW-2228), A Human G-CSF Derivative with Higher Specific Activity
Nippon Nōgeikagaku Kaishi·1996Open Access
Stabile production of a thrombin resistant pro-urokinase derivative (PRO-UKS1) by Namalwa KJM-1 cells adapted to serum-free medium
Cytotechnology·1996· 5 cited
Stable production of recombinant pro-urokinase by human lymphoblastoid Namalwa KJM-1 cells: Host-cell dependency of the expressed-protein stability
Cytotechnology·1993· 11 cited
Stable Production of Pro-urokinase and its Derivative by Namalwa KJM-1 Cells Adapted to a Serum-free Medium
1993· 2 cited
Qualitative Improvement of Therapeutic Glycoproteins by Glycotechnology.
Trends in Glycoscience and Glycotechnology·1992· 5 cited
Expression of salmon growth hormone in the cyanobacteriumAgmenellum quadruplicatum
Biotechnology Letters·1991· 15 cited
Optimization of cell culture conditions for G-CSF (granulocyte-colony stimulating factor) production by genetically engineered namalwa KJM-1 cells
Cytotechnology·1991· 15 cited
Optimization of cell culture conditions for production of biologically active proteins
Cytotechnology·1991· 16 cited
Efficient expression of human beta-interferon in Namalwa KJM-1 cells adapted to serum-free medium by a dhfr gene coamplification method
Cytotechnology·1990· 16 cited
Expression of human lymphotoxin in Namalwa KJM-1 cells adapted to serum-free medium
Cytotechnology·1990· 8 cited
Expression of human beta-interferon in Namalwa KJM-1 which was adapted to serum-free medium
Cytotechnology·1990· 25 cited
Effect of N-terminal deletion of signal peptide on the secretion of human granulocyte-colony stimulating factor in mammalian cells
Biotechnology Letters·1990· 4 cited
Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells
International Immunology·1990· 91 cited
Creation of new drugs by protein engineering.
Kobunshi·1990· 1 citedOpen Access
Isolation and characterization of a novel growth hormone cDNA from chum salmon (Oncorhynchus keta)
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression·1989· 28 cited
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Frequent Co-authors

Tatsunari Nishi(14), Tamio Mizukami(12), Hiromasa Miyaji(10), Akiko Saito(8), Moriyuki Sato(8), Takeo Suzuki(7), Susumu Sekine(7), Tadatsugu Taniguchi(6), Seiji Sato(6), Tetsurō Kuga(5), Tetsuo Oka(5), Mitsuo Satoh(5), Yoshihisa Kuwana(4), Hiroshi Kawauchi(4), Yoshinori Komatsu(4), Motoo Yamasaki(4), Yoshiharu Yokoo(4), Chikako Takaoka(4), Nobuo Fujiyoshi(4), Shinji Hosoi(3)